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This paper concerns the design and implementation of a new implantable Neuro-Monito-Stimulation System (NMSS) for the urinary tract rehabilitation in paraplegics. In addition to selective stimulation for voluntary micturition and permanent stimulation for reduction of the detrusor overactivity, the NMSS includes telemetry capabilities of electrodes-tissues contact. Resistance up to 10 kOmega could...
This paper presents techniques developed for the extraction of biological information in a recently developed hand-held biochip-based microsystem. The microsystem is based on a magneto-resistive array biochip composed of a number of sensing sites with magnetic tunnelling junctions (MTJ) and diodes. To drive the MTJ, different techniques are addressed with different types of signals. Different filtering...
Video microscopic platforms have been developed to capture cell dynamics, such as cell velocity, in real-time to quantify and usefully leverage the electro kinetic response of cells to electric fields. The first and critical task in a cell motion detection algorithm is the computationally demanding segmentation process, where a static cell boundary aids grouping the cell regions and thereby identifying...
This paper describes the design of silicon intracortical stimulating microelectrodes for mapping of the functional organization in the central nervous system and potential neural prosthetic applications. Active microelectrodes with different configurations have been developed to facilitate various applications. In-vivo experiments were conducted in selected areas (auditory cortex, DCN, IC) in the...
A 402-405 MHz MICS band transceiver has been developed for implantable medical applications. The transceiver offers exceptionally low power consumption whilst providing a high data rate. The circuit features a unique ultra low power wakeup system enabling an average sleep current of less than 250 nA. The transmit and receive current is less than 5 mA when operating at a data rate of up to 800 kbps...
A system to remotely monitor a patientpsilas oxygen saturation (%SpO2) levels is described. The data was continuously measured using a pulse oximeter and then transferred to a central monitoring station via a wireless sensor network for storage and display. Crossbow MICAz motes were programmed to serve as the network nodes. One mote was interfaced to the pulse oximeter for data acquisition and the...
This paper intends to reduce the power dissipation of the GICam image compressor for capsule endoscope or swallowable imaging capsules while the gastrointestinal images are cardinal. In order to further extend the battery life of capsule endoscope, we firstly attempt to analyze the energy distribution and variation of DC/AC coefficients in 2D-DCT domain for twelve tested GI images. According to the...
This paper proposes a batteryless, wireless communication circuit, which is designed to be combined with a hydrogen ion exponent (pH) sensor for the measurement of gastric acid. The proposed circuit converts the output of the biosensor into a pulse interval modulation (PIM) code and transmits the code to a base station. The circuit is powered solely by the base station via inductive coupling. Simulation...
The following topics are dealt with: biosensor devices and interface circuits; low power biomedical signal processing circuits; biosignal classification; biosignal recognition; bioinformatics healthcare management; biomedical instrumentation; healthcare radio technology; assistive technology for the disabled; implantable device monitoring; stimulation electronics; neural interface circuits; and cardiovascular...
In this paper a simple low cost measurement system of electrocardiogram (ECG) is presented. It is implemented by digitizing the measured ECG signal and then wireless (infrared) transmitting to be displayed the result on the computer screen. The analog-to-digital converter of the proposed method is based on a simple sigma-delta modulator. The main advantage of this circuit is that it has noise-shaping...
An abdominal aortic aneurysm (AAA) is a dilatation of the aorta at the abdominal level, which rupture is a life threatening complication. Recent treatment of AAA consists in endovascular treatment with covered stent grafts. Despite improving devices, this treatment is still associated with close to 25% of failure related to persisting pressure into the excluded aneurismal sac. The follow-up becomes...
It has been accepted by some researchers that pulse transit time (PTT) is correlated with arterial blood pressure (ABP). However, the applications of PTT-based approach for BP measurement are limited due to the lack of convenient calibration method. This paper aims to propose an innovative model-based calibration system, which makes use of pressure change during air deflation of arm cuff to obtain...
This paper describes the implementation of a prototype platform designed for the experimentation in the development of a non-invasive retinal prosthesis. The platform presented here is highly programmable and reconfigurable as required for experimentation. It provides retinomorphic encoding and optoelectronic stimulation. The purpose of the project is to develop, in the near future, an optoelectronic...
Electroencephalographic (EEG) analysis has been widely adopted for the monitoring of cognitive state changes and sleep stages because abundant information in EEG recording reflects changes in drowsiness, arousal, sleep, and attention, etc. In this study, micro-electro-mechanical systems (MEMS) based silicon spiked electrode array, namely dry electrodes, are fabricated and characterized to bring EEG...
This paper presents a wireless high throughput data transmission system dedicated to interface implantable multi-channel neural recording devices. Its main component is a low-end wireless IEEE 802.11g compliant LAN router, which makes it very cost effective and reliable. The presented design is portable/wearable and, therefore, well suited for high data rate medical systems applications. Furthermore,...
A bandage based thermometer placed on the temple region of the forehead provides an non-invasive means of measuring a patientpsilas core body temperature. An array of temperature sensors spaced along the length of the bandage is used to determine the skin temperature over the temporal artery. Temperature sensors buried within the bandage allow the direct measurement of the heat flow leaving the skin...
Identification of the inferior alveolar nerve in the mandible is extremely important in dental implantology. With computed tomography (CT), a series of panoramic images can be generated by reformatting the three-dimensional axial data so that the alveolar nerve canals are visible in the tabular-like form on the panoramic images. Due to a rather complicated structure of the alveolar nerve, existing...
In this paper, a new automated early-stage detection of heart defect is introduced. Based on the proposed technique, human heart is modeled as a pump system where ECG signal and PCG signal are defined to be command (input) and response (output) of the system, respectively. The ratio of discrete Fourier transform of both signals is employed to determine the transfer function Hp(k) of a patientpsilas...
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