The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The self-assembly and deposition mechanisms of nanoparticles in droplets on a substrate are significant in many inkjet printing-based industrial applications such as microelectronics, display systems, and paint manufacturing. In this study, we describe the underlying lack mechanisms of the self-assembly and deposition behavior of nanoparticles in inkjet-printed. We also demonstrate the development...
An intraocular implantable magnetically actuated micropump for drug delivery is proposed. A magnetic nanoparticle-PDMS composite membrane assembly in the micropump can be actuated in magnetic field, and it causes drug release. The membrane assembly is composed of thin elastic PDMS membrane and thick magnetic nanoparticle-PDMS composite (MNPC) to obtain maximum deflection of membrane within the confined...
In this study, we propose a nanofluidic power generator inspired by an electrical eel to harness ion concentration gradient by reverse electrodialysis (RED). The key element for nanofluidic device, cation-exchange NCNM (CE-NCNM) and anion-exchange NCNM (AE-NCNM) constructed by self-assembled nanoparticles with hydroxyl and amine groups, respectively, enable high ionic current through 3-dimensional...
Nowadays, the interest about the implantable or wearable devices has increased rapidly. Due to these attentions, it becomes greatly important issue to develop long-term powering and recharging of implantable devices through a safe, efficient and convenient way and there have been several developments about power sources for implantable devices such as batteries, nuclear cell, bio-fuel cell, etc. Especially,...
Research interest on transportation of ion through nanoscale geometries has increased recently due to its emerging applications such as energy harvesting, biomolecule concentration/separation, water purification, chemical mixing etc. Besides of application studies using ion transportation, the fundamental research for revealing and understanding mechanism has been carried out by many research groups...
In this study, we demonstrate that drug treatments change cardiomyocyte contractile force in vitro. Contractile force was determined by bending deflection of the cantilever end. We quantified the effect of Digoxin, Isoproterenol, and BayK8644, drugs that increase contractile force, on cardiomyocyte contractile forces when grown on the grooved cantilever. We also investigated the effect of Verapamil,...
This paper presents a novel microplatform for high power energy generation based on reverse electrodialysis. The effective cation-selective membrane for power generations is realized between two microfluidic channels using geometrically controlled in situ self-assembled nanoparticles with cost-effective and simple way. Nano-interstices between the assembled nanoparticles have a role as the collective...
Cell therapy has been studied a lot to apply to cranial nerve degenerative diseases. But overcoming limitation of low survival rate of transplanted cells is the important thing for cell therapy. For this, studies of transplanting cells in spheroid type are under way. However, the characteristic of cell spheroid is not grasped yet. General MEA can get signals only on a single contact spot with neurospheroid,...
In this study, we propose a novel microplatform to study nanoscale electrokinetics in fluid, that is, ion transportation on nanoscale or microscale. This system is constructed by fine control of self-assembly of nanoparticles in microchannel. We use this assemble particles as an ion-selective membrane and carry out the analysis about ion depletion layer formation according to the changes of geometry...
We present a robust microfluidic platform for stable generation of multiple chemical gradients simultaneously using in situ self-assembly of microparticles in microchannels and show the potential of the proposed system for analysis of bacterial preference for cancer cell secreting proteins. We demonstrate the proof of concept as a preferential chemotaxis assay of bacteria toward multiple chemical...
In this study, we propose a novel technique for fine control of self-assembly of nanoparticles in microchannel and use it as an ion-selective membrane. In order to characterize the electrokinetic phenomena at the interface between the assembled membrane and microchannel, the ion depletion layer formation according to the changes of geometry of microchannels, and size and materials in nanoparticles...
This paper proposes a new technique for protein detection using quenching effects from aptamer-functionalized photonic crystals. The surface of hydrogel based inverse opal structures are functionalized with aptamers and they are hybridized with quenchers. Then, target protein (thrombin) can be selectively, sensitively detected by monitoring the change of both intensity and color (change of reflective...
This paper reports a novel method for in-situ geometrically controlled self-assembly of colloidal crystals within microchannel using ‘one step stamping’. and its application for seawater desalination process by ion concentration polarization.
Formation of membranes in microfluidic channels have been paid attention for their great potentials in separation of components, cell culture supports for tissue engineering and chemical process involving molecular transports. In this study, we introduce a few techniques for formation of hydrogel membranes in microfluidic channels and their applications. First, using enzymatically crosslinkable hydrogels...
Photonic crystal (PC) based biosensors have been attracted more attention due to their advantages, such as sensitivity, real time monitoring and low-cost realization. Especially, label-free PC bioassay is more attractive than labeling detection, because time-consuming and expensive labeling step for the targets can be eliminated. Point-of-care testing is possible without fluorescent equipments and...
The use of membranes within microfluidics has been widely studied, such as separating of components and culturing supports of scaffolds for tissue engineering. A few methods for in-situ formation of membranes have been reported. However, these methods are hard to control the width of membrane or difficult to realize stable interfacial membranes. Furthermore, these conventional methods are impossible...
This paper reports a novel method for the in-situ hydrogel membrane fabrication in a simple PDMS channel. We used two separate solutions of 0.0625 wt% of H2O2 in PBS with the 5.2 wt% of the Tetronic-succinic anhydride-tyramine (Tet-SA-TA), and 0.0625 mg/ml of horseradish peroxidase (HRP) in PBS with the same concentration of Tet-SA-TA. These two solutions were introduced into the typical microfluidic...
This paper reports a biomimetic humidity sensor inspired by the humidity-dependent color change observed in the cuticle of the Hercules beetle. A film-type humidity sensor with nanoporous structures based on 3D photonic crystals was designed and fabricated using the colloidal templating method and a surface treatment. The visible color of the fabricated humidity sensor changes from blue-green to red...
Nowadays, green technology solution using natural power such as solar, wind, waves et al. has been interested as an alternative power source instead of battery. This paper presents a portable power source driven by natural wind power. One of very efficient energy conversion mechanisms to change mechanical energy of natural power with electrical energy is a direct piezoelectric effect. However, this...
We present a novel MEMS-based power generator using activation of cardiomyocytes. Cardiomyocytes are cultured on the MEMS fabricated lead magnesium niobate-lead titanate (PMN-PT) single crystal diaphragm, directly and the mechanical stress induced by contraction forces from cardiomyocytes is conversed into electrical power. This PMN-PT single crystal diaphragm has one-side interdigitated electrode...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.