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Thermoplastic is a common material in industrial products and it can be applied to microfluidic application since it is much more affordable and stable than PDMS in vary aspects. Based on former studies, a manufacturing process of thermoplastic microfluidic system is proposed, from the feature design to the final microfluidic device. The protocol being proposed is able to achieve rapid prototyping...
In this work, a technological solution is proposed for the fast and low cost realization of autonomous capillary systems that can operate with saline solutions typically used for the implementation of bioanalytical protocols. In order to develop and test the technological process, a simple microfluidic network has been designed. The network includes elementary structures as mixers, T-junctions and...
As designers of MEMS and bioMEMS strive for increased device performance and are exploring more exotic material systems, which may not be compatible with conventional photolithographic processes; techniques that can circumvent the limitations of conventional fabrication processes can offer new pathways for the creation of high impact devices. Microfluidic processes can provide precision control of...
This paper presents low-cost plastic micromolds fabricated by X-ray LIGA technology. High aspect ratio microstructures are constructed by X-ray lithography process and used as a master mold for microfluidic systems. The master mold is replicated by PDMS to be used as the second mold and then transferred their patterns to plastic mold using casting method. Finally, the plastic mold performs itself...
This paper uses a simple, fast, and low-cost method to fabricate an arrayed flexible glucose biosensor device. The ruthenium dioxide sensing membranes were deposited on the flexible polyethylene terephthalate substrate by radio frequency sputtering technology. The silver paste was fabricated as conducting wire and the epoxy was fabricated as insulation layer by screen-printed technique...
Metallic microchannel mold for microfliudic applications is demonstrated based on X-ray LIGA technology. High aspect ratio microchannel made of SU-8 photoresist was constructed on a stainless substrate to create a mold template using X-ray lithography generated by synchrotron light source. Following X-ray lithography, the SU-8 mold template was filled with electroplated nickel to produce the required...
This paper presents the first results of the fabrication and characterization of a biological sensor based on two complementary parts. A microfluidic channel along with a micromachined stop-band filter are used to detect the type of fluid which flows beneath the electronic circuit. The tridimensional (3D) structure of the microstrip technology is integrated using SU8 material which thus supports the...
Polymers are widely used for microfluidic systems, but fabrication of microarrays on such materials often requires complicated chemical surface modifications, which hinders the integration of microarrays into microfluidic systems. In this paper, we demonstrate that UV irradiation can be used to directly immobilize poly(T)poly(C)-tagged DNA oligonucleotide probes on non-modified plastic surfaces. This...
We reports the experimental results of the novel polygonal microstructures self-assembled from the evaporating picoliter droplets in micro-scale cavities. Utilizing the inkjet-like method, the drop-on-demand (DOD) droplets of colloidal polymers (Polyurethane, PU 15% in volume) can be precisely positioned into the constrained regions on the polymeric (Polydimethysiloxane, PDMS) substrates which are...
This work presents the design, theory, and measurement of a linearly polarized microstrip patch antenna with a substrate-integrated compensation mechanism to mitigate the detuning effects from a physical deformation (e.g., bending and twisting). In particular, we investigate the ability of an antenna to maintain its impedance bandwidth as it bends sharply through the center (from flat up to 90deg...
Here we report on dynamic patterning of nanoparticles in microfluidic channels using patterned surface plasmon polaritons (SPP) from a gold thin film with highly ordered nanohole arrays. In particular, the constructive interference of SPPs from neighboring holes leads to a periodic distribution of SPP intensities. Such a SPP distribution drives the nanoparticles into positions of minimal SPP intensities,...
This paper presents a novel bonding-free process for fabricating integrated microfluidic devices with embedded electrodes utilizing low-cost UV curable resins. Commercial available UV glue is sandwiched between two substrates and is used for both the structure material and bonding adhesive. The pattern of micro-fluidic channels is defined using a standard lithography process while two substrates are...
Presently, with the development of nanofabrications, patterning nanoparticles into monolayer attracts tremendous interests. In this work, a microfluidic-assisted nanoparticle monolayer patterning approach was proposed to produce noncontinuous patterns based on the well-known continuity equation in fluid mechanics. Soft-lithography used in this approach greatly reduced the cost and time of the fabrication...
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