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A nanostructured layer-by-layer (LBL) dip coating method for silicone catheters was developed and optimized for prolonged release of chlorophene to help prevent urinary tract infections often complicated from extended use of catheters. The coating technique comprised alternating layers of drug-loaded poly(ethylene glycol)-block-poly(??-caprolactone) (PEG-b-PCL) micelles and poly(acrylic acid) (PAA)...
The disinfectant loaded micelle fabrication were investigated as a carrier for 2-benzyl-4-chlorophenol (OBPCP), a disinfectant agent. Micelles were assessed in terms of the drug entrapment efficiency by suitable fabrication process. Results showed that a film sonication method provided the highest drug loading density at 16.35 ± 0.52%. To utilize numerous advantages of these polymer micelles, micelles...
We demonstrate a novel localized surface plasmon resonance based sensor that can differentiate a target interaction from interfering interactions. This is accomplished by the simultaneous interrogation of the sensing medium with the multiple surface plasmon modes of the U-shaped gold nanostructure.
Atomic Force Microscopy (AFM) is a powerful tool that can perform nano-scale imaging. Normally AFM tip is controlled to scan on sample surface line by line to get the topographic image and this process takes several minutes. Higher sample rate is demanded so that when doing continuous imaging, the time interval between each image can be significantly shorted thus video-imaging can be achieved. In...
Integration of waveguides and microfluidic channels enables construction of weak fluorescence detection system at a chip size. Crossed structure of a waveguide and a microfluidic channel can achieve small detection volume, which contributes to reduction of sample consumption and separation of each molecule. The decrease of defects caused by fabrication processes is indispensable because of efficient...
We developed a methodology for the design and fabrication of silicon nanowire-based circuits. Starting from a functional description of the circuit and using technological data, we generated the physical design of the described function by placing nanowires, FETs and connections. We modeled each circuit sub-block considering resistances, capacitances and FET currents, taking into account gate quantum...
Novel approach to control of photoelectron processes is based on nanoscale engineering of 3D potential profile employing quantum dots with built-in charge (Q-BIC). Charging of quantum dots creates local potential barriers around single dots, if dots are arbitrary distributed in the medium, and collective barriers around dot clusters, rows etc, if quantum dots form specific structures. Manipulations...
This paper puts forward an enabling transistor sizing scheme targeting classical CMOS gates when implemented in advanced technologies. It relies on the well-known CMOS inverter for introducing the novel sizing concepts as well as for preliminary simulations verifying these concepts and comparing the resulting performances. These preliminary simulations support the claim that sizing has yet some potential...
Static mechanical error is a key factor that must be taken into account for multi-axis measuring equipments in precision measurement. Many static mechanical error sources are analyzed in the paper with computer-aided modeling method, and the error correction method is also discussed based on error modeling. Based on the above mentioned mathematical models, a computer four-axis virtual analysis platform...
This paper presents a novel multi-slicing of Caenorhabditis elegans (C. elegans) tissue using micro-nanocutting probe based on nanomanipulation. We have developed the nanorobotic manipulation system inside an Environmental-Scanning Electron Microscope (E-SEM). This microscope provides a real-time high resolution image under water-contained condition. We have been applied this system for nanobiomanipulation,...
Uniform, 2 nm diameter gold nanowires were synthesized through the reduction of gold(III) chloride in an oleylamine matrix. They were top-contacted on a Si/SiO2 substrate with metallic electrodes to manufacture back-gated transistors. Due to thermal breakage, the gold nanowires were fragmented into a granular material and the non-linear current-bias voltage characteristics measured on the devices...
This paper reports a thermal sensor assembled by two multi-walled carbon nanotubes (MWCNTs) inside a field emission scanning electron microscope (FESEM) which constructed a probe tip in order to detect the local environment of single cell. An atomic force microscope (AFM) cantilever was used for substrate which is composed by Si3N4, and double side was covered by gold layer. Two MWCNTs were assembled...
Boron carbide is widely used materials for its attractive combination of properties such as high hardness, low density, high melting point, excellent thermoelectric properties, etc. As well, sintered boron carbide is commonly used, also its powder is applicable for many areas of industry. The aim of study was produce nanopowders and dense bodies of B4C via Spark Plasma Sintering (SPS). Fast and effective...
A novel two-step batch process was invented to prepare BaTiO3 ceramic nanoparticles of high quality in supercritical fluids. Firstly, reactants were heated up in a proper organic solvent until target temperature and pressure were reached. Secondly, water was injected into the above organic solvent to form a supercritical mixing solvent. After a certain period of treatment in the supercritical state,...
Printed electronics is expected to be a low-cost, eco-friendly, and on-demand fabrication technology because it decreases the number of process steps and the amount of waste materials. Carbon nanotube (CNT) transistor arrays were fabricated on plastic films by maskless printing without any additional pattering process, and minimum materials were used. During fabrication, the morphology of the CNT...
Nano diodes show great potential for applications in detectors, communications and energy harvesting. However, to make them suitable for low-cost mass production, these nano devices have to be fabricated reliably over large areas while minimizing process time and costs. Printing techniques are promising candidates to overcome these economical drawbacks of conventional nanolithography without a significant...
DNA methylation is an important cancer biomarker, but improving the detection sensitivity of DNA methylation remains a challenge for various types of biological samples. Here, we describe a novel quantum dot (QD)-based method using FRET linker probes (FLPs) that further increases the sensitivity of detection of DNA methylation patterns. This method relies on removing the background noise resulting...
In this paper, vertically aligned ZnO nanowire arrays were synthesized by a simple hydrothermal process. The microstructure, morphology, magnetic and optical properties of the as-prepared samples were characterized by x-ray diffraction (XRD), scanning electron microscope (SEM), vibrating sample magnetometer(VSM) and photoluminescence spectrum (PL). The results show that the vertically aligned ZnO...
The effect of oxygen-containing defects on the adsorption onto plasma-treated single- walled carbon nanotubes (SWCNTs) of two peptide sequences known to bind to the CNT surface was investigated using chemiresistor-type SWCNT devices. A peptide with highly selective affinity for SWCNTs was designed and its mutated peptide was used as a control to compare the adsorption effect on the SWCNTs. The oxygen...
Poly(tetra phenyl ether sulfone)s (PTPES) were functionalized with quaternary ammonium salt groups in order to investigate their properties as novel polymeric hydroxide exchange membrane materials. The PTPES-QAH (quaternary ammonium hydroxide)s were synthesized via chloromethylation of PTPESs, followed by reactions with chloromethylmethylether and ZnCl2, SOCl2 as Lewis acid catalyst, and then quaternized...
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