Search results for: Takayuki Nakamura

Items from 1 to 20 out of 76 results

article

Successful correction of factor V deficiency of patient‐derived iPSCs by CRISPR/Cas9‐mediated gene editing

Takayuki Nakamura, Satoshi Morishige, Hidetoshi Ozawa, Kenji Kuboyama, more

Background Factor V (FV) deficiency is a monogenic inherited coagulation disorder considered to be an ideal indication for gene therapy. To investigate the possibility of therapeutic application of genome editing, we generated induced pluripotent stem cells (iPSCs) from a FV‐deficient patient and repaired the mutation of factor V gene (F5) using a clustered regularly interspaced short palindromic...

article

Complete response following toxic epidermal necrolysis in relapsed adult T cell leukemia/lymphoma after haploidentical stem cell transplantation

Satoshi Morishige, Marina Nishi, Hiroshi Saruta, Fumiko Arakawa, more

International Journal of Hematology > 2019 > 110 > 4 > 506-511

Allogeneic hematopoietic cell transplantation (allo-HSCT) is considered the curative treatment option in patients with aggressive adult T cell leukemia/lymphoma (ATLL), but the treatment of relapse after allo-HSCT remains a major challenge. We report a case of ATLL that was treated with sequential mogamulizumab (MOG) and lenalidomide (LEN) for early relapse after allo-HSCT. A 73-year-old Japanese...

article

Distance estimation with 2.5D anchors and its application to robot navigation

Hirotaka Hachiya, Yuki Saito, Kazuma Iteya, Masaya Nomura, more

ROBOMECH Journal > 2018 > 5 > 1 > 1-13

Estimating the distance of a target object from a single image is a challenging task since a large variation in the object appearance makes the regression of the distance difficult. In this paper, to tackle such the challenge, we propose 2.5D anchors which provide the candidate of distances based on a perspective camera model. This candidate is expected to relax the difficulty of the regression model...

article

The tibial growth plate as a predictor of the original tibial plateau joint line as a reference for kinematically aligned total knee arthroplasty

Katsuya Nagai, Yasuo Niki, Kengo Harato, Shu Kobayashi, more

Journal of Orthopaedic Surgery and Research > 2018 > 13 > 1 > 1-5

Background Restoration of the natural joint line is a cornerstone for kinematically aligned total knee arthroplasty (TKA). The purpose of this study was to investigate the relative orientation of the tibial growth plate (GP) with respect to the tibial plateau (TP) for possible application in predicting natural joint line for knees with highly advanced osteoarthritis patient at the time of kinematically...

article

Sleep-disordered breathing and disorders of glucose metabolism

Tomoyuki Kawada, Masao Katsumata, Hirofumi Inagaki, Takayuki Nakamura, more

Diabetes & Metabolic Syndrome: Clinical Search and Reviews > 2017 > 11 > 3 > 189-191

The authors identified the risk of disorders of glucose metabolism (DGM) for sleep-disordered breathing (SDB).We conducted a cross-sectional study in 536 men aged 33–84 years. Patients with diabetes medication were excluded for the analysis and DGM were diagnosed by fasting plasma glucose≥100mg/dl and/or 2h plasma glucose ≥140mg/dl.The prevalence of DGM in subjects with and without severe SDB, which...

chapter

Novel crosstalk evaluation method for high-density signal traces using clock waveform conversion technique

Takayuki Nakamura, Koji Asami

2016 IEEE International Test Conference (ITC) > 1 - 7

2016 IEEE International Test Conference (ITC)

Today, as LSI devices are increasingly more integrated resulting in larger number of package pins, high speed signal lines are more easily coupled to each other. Additionally, since multisite testing is required to reduce the cost of test, the transmission lines connecting these pins become even more concentrated. To measure these LSI devices, a huge number of high-speed transmission lines are required...

chapter

Clarification of no-load loss in DC-DC converter

Takayuki Nakamura

IECON 2016 - 42nd Annual Conference of the IEEE Industrial Electronics Society > 1307 - 1312

IECON 2016 - 42nd Annual Conference of the IEEE Industrial Electronics Society

To improve the efficiency of DC-DC converters, this paper focuses on air-core reactors. First, the author deduces the relation between load loss and no-load loss, which originates from ripple current. Next, the author tests a reactor regarding the increase in temperature by changing the waveforms and frequencies under the same cooling and rms current conditions that enable the separation of the DC...

article

Angiopoietin-like protein 2 induces interleukin-6 expression in the mechanism underlying ligamentum flavum hypertrophy in lumbar spinal canal stenosis patients

Takayuki Nakamura, Kazuki Sugimoto, Hiroshi Mizuta

Journal of Orthopaedic Translation > 2016 > 7 > C > 94

chapter

Development of self-learning vision-based mobile robots for acquiring soccer robots behaviors

Takayuki Nakamura

Lecture Notes in Computer Science > RoboCup-97: Robot Soccer World Cup I > 257-276

An input generalization problem is one of the most important ones in applying reinforcement learning to real robot tasks. To cope with this problem, we propose a self-partitioning state space algorithm which can make non-uniform quantization of the multidimensional continuous state space. This method recursively splits its continuous state space into some coarse spaces called tentative states. It...

chapter

The Proposal of Service Delivery Platform Built on Distributed Data Driven Architecture

Jianfeng Zhang, Yuki Kishikawa, Kentaro Fujii, Yousuke Kouno, more

Lecture Notes in Computer Science > Management Enabling the Future Internet for Changing Business and New Computing Services > Converged Networks and Traffic Engineering > 201-210

SDP (Service Delivery Platform) is a recommended system platform for NGN (Next Generation Network) that is expected to resolve two common system running problems: one is functional aspects such as high availability and providing effective maintenance methods, the other is cost aspects such as simplifying development method of a service. However, SDP is still on the way to be standardized, and its...

chapter

Classifier Acceleration by Imitation

Takahiro Ota, Toshikazu Wada, Takayuki Nakamura

Lecture Notes in Computer Science > Computer Vision – ACCV 2010 > Posters on Day 3 of ACCV 2010 > 653-664

This paper presents a framework named “Classifier Molding” that imitates arbitrary classifiers by linear regression trees so as to accelerate classification speed. This framework requires an accurate (but slow) classifier and large amount of training data. As an example of accurate classifier, we used the Compound Similarity Method (CSM) for Industrial Ink Jet Printer (IIJP) character recognition...

chapter

A Method for Localization by Integration of Imprecise Vision and a Field Model

Kazunori Terada, Kouji Mochizuki, Atsushi Ueno, Hideaki Takeda, more

Lecture Notes in Computer Science > RoboCup-99: Robot Soccer World Cup III > Technical Papers > 509-518

In recent years, many researchers in AI and Robotics pay attention to RoboCup, because robotic soccer games needs various techniques in AI and Robotics, such as navigation, behavior generation, localization and environment recognition. Localization is one of the important issues for RoboCup. In this paper, we propose a method of robot’s localization by integrating vision and modeling of the environment...

article

Relationship between sleep-disordered breathing and metabolic syndrome after adjustment with cardiovascular risk factors

Tomoyuki Kawada, Toshiaki Otsuka, Takayuki Nakamura, Yoichi Kon

Diabetes & Metabolic Syndrome: Clinical Search and Reviews > 2016 > 10 > 2 > 92-95

It is important to identify the risk factors for metabolic syndrome (MetS) in order to prevent the development of cardio-/cerebrovascular diseases. The authors estimated the risk factors for the development of MetS with special emphasis on the severity of sleep-disordered breathing (SDB).We conducted as a cross-sectional study in subjects undergoing intensive health examination (581 men aged 33–84...

article

Analysis of the mixing state of airborne particles using a tandem combination of laser-induced fluorescence and incandescence techniques

Fumikazu Taketani, Yugo Kanaya, Takayuki Nakamura, Naoki Takeda, more

Journal of Aerosol Science > 2015 > 87 > C > 102-110

We have developed a novel system for real-time measurement of the mixing state of aerosol particles using a tandem combination of laser-induced fluorescence (LIF) and incandescence (LII) techniques. The tandem analysis system comprises two chambers connected in series; particles are analyzed with LIF in the first chamber and LII in the second chamber. We analyzed identical particles using the two...

chapter

Acquisition of human operation characteristics for kite-based tethered flying robot using human operation data

Chiaki Todoroki, Yasutake Takahashi, Takayuki Nakamura

2015 IEEE International Conference on Fuzzy Systems (FUZZ-IEEE) > 1 - 7

2015 IEEE International Conference on Fuzzy Systems (FUZZ-IEEE)

This paper shows human skill acquisition systems to control the kite-based tethered flying robot. The kite-based tethered flying robot has been proposed as a flying observation system with long-term activity capability[1]. It is a relatively new system and aimed to complement other information gathering systems using a balloon or an air vehicle. This paper shows some approaches of human operation...

article

Local Application of Gelatin Hydrogel Sheets Impregnated With Platelet-Derived Growth Factor BB Promotes Tendon-to-Bone Healing After Rotator Cuff Repair in Rats

Takuya Tokunaga, Junji Ide, Hitoshi Arimura, Takayuki Nakamura, more

Arthroscopy: The Journal of Arthroscopic and Related Surgery > 2015 > 31 > 8 > 1482-1491

To determine whether the local application of platelet-derived growth factor BB (PDGF-BB) in hydrogel sheets would promote healing and improve histologic characteristics and biomechanical strength after rotator cuff (RC) repair in rats.To assess the effect of PDGF-BB on tendon-to-bone healing we divided 36 adult male Sprague-Dawley rats treated with bilateral surgery to repair the supraspinatus tendon...

article

Reduction of Ripple Current Loss by Electromagnetic Coupling of Air‐Core Reactors

Takayuki Nakamura, Yoshiaki Taguchi, Masamichi Ogasa

Electrical Engineering in Japan > 193 > 2 > 69 - 81

To reduce the loss due to ripple current in a multiphase current‐reversible chopper, we investigated electromagnetic coupling of an air‐core reactor. We derived the relationship between the amplitude of the ripple current, the duty factor, and the electromagnetic coupling coefficient, and used the results to estimate the effects of electromagnetic coupling in the design of a train energy storage system...

article

Patient outcomes for a minimally invasive approach to treat lumbar spinal canal stenosis: Is microendoscopic or microscopic decompressive laminotomy the less invasive surgery?

Toru Fujimoto, Takuya Taniwaki, Shogo Tahata, Takayuki Nakamura, more

Clinical Neurology and Neurosurgery > 2015 > 131 > Complete > 21-25

We performed a study to compare the severity of surgical stress between microscopic and microendoscopic decompressive laminotomy performed via a unilateral approach in patients with lumbar spinal canal stenosis (LSCS).A total of 41 patients received decompressive laminotomy for lumbar spinal stenosis. Twenty patients received microscopic decompressive laminotomy (MDL), and 21 patients received microendoscopic...

chapter

Novel three dimensional (3D) CD-SEM profile measurements

Makoto Yoshikawa, Benjamin Bunday, Longhai Liu, Wataru Ito, more

2015 China Semiconductor Technology International Conference > 1 - 3

2015 China Semiconductor Technology International Conference (CSTIC)

A new SEM technology, Advantest's Wafer MVM-SEM E3310, is becoming available that allows quantitative, image-based 3D profile metrology of nanoscale features. CD-AFM is generally employed for 3D profile information, but this technique has its own limitations for 1Xnm node production due to tip size constraints in the tightest spaces, and due to finite tip lifetime which can influence measurement stability...

article

Angiopoietin-like protein 2 promotes inflammatory conditions in the ligamentum flavum in the pathogenesis of lumbar spinal canal stenosis by activating interleukin-6 expression

Takayuki Nakamura, Tatsuya Okada, Motoyoshi Endo, Takafumi Nakamura, more

European Spine Journal > 2015 > 24 > 9 > 2001-2009

Purpose Chronic inflammation is thought to cause ligamentum flavum (LF) degeneration and hypertrophy in lumbar spinal canal stenosis (LSCS). Angiopoietin-like protein 2 (Angptl2) is highly expressed in hypertrophied LF. Because Angptl2 regulates interleukin-6 (IL-6) expression in various tissues, we investigated whether IL-6 is expressed in hypertrophied LF and, if so, does Angptl2 induce IL-6 expression...

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INFONA - science communication portal

Search results for: Takayuki Nakamura

Successful correction of factor V deficiency of patient‐derived iPSCs by CRISPR/Cas9‐mediated gene editing

Complete response following toxic epidermal necrolysis in relapsed adult T cell leukemia/lymphoma after haploidentical stem cell transplantation

Distance estimation with 2.5D anchors and its application to robot navigation

The tibial growth plate as a predictor of the original tibial plateau joint line as a reference for kinematically aligned total knee arthroplasty

Sleep-disordered breathing and disorders of glucose metabolism

Novel crosstalk evaluation method for high-density signal traces using clock waveform conversion technique

Clarification of no-load loss in DC-DC converter

Angiopoietin-like protein 2 induces interleukin-6 expression in the mechanism underlying ligamentum flavum hypertrophy in lumbar spinal canal stenosis patients

Development of self-learning vision-based mobile robots for acquiring soccer robots behaviors

The Proposal of Service Delivery Platform Built on Distributed Data Driven Architecture

Classifier Acceleration by Imitation

A Method for Localization by Integration of Imprecise Vision and a Field Model

Relationship between sleep-disordered breathing and metabolic syndrome after adjustment with cardiovascular risk factors

Analysis of the mixing state of airborne particles using a tandem combination of laser-induced fluorescence and incandescence techniques

Acquisition of human operation characteristics for kite-based tethered flying robot using human operation data

Local Application of Gelatin Hydrogel Sheets Impregnated With Platelet-Derived Growth Factor BB Promotes Tendon-to-Bone Healing After Rotator Cuff Repair in Rats

Reduction of Ripple Current Loss by Electromagnetic Coupling of Air‐Core Reactors

Patient outcomes for a minimally invasive approach to treat lumbar spinal canal stenosis: Is microendoscopic or microscopic decompressive laminotomy the less invasive surgery?

Novel three dimensional (3D) CD-SEM profile measurements

Angiopoietin-like protein 2 promotes inflammatory conditions in the ligamentum flavum in the pathogenesis of lumbar spinal canal stenosis by activating interleukin-6 expression

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