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A nanoscale semiconducting ZnO based biosensor with integrated microfluidics is designed, fabricated and tested to demonstrate the detection of streptavidin, a commonly used protein. Amperometric (I-t) measurement is utilized to detect the change of conductivity over time. By comparing with the control experiment, the specific binding event between biotin and streptavidin is detected. The data indicates...
There is an increasing demand for portable, reliable, and cost effective bioelectronic systems for applications ranging from clinical diagnosis to homeland security. Conventional detection systems involve labeling the probe molecules, large amount of target molecules to enable detection, and elaborate signal transduction methods. Most of them also have to couple with optical detection equipments that...
A nanobioelectronic system-on-package (SOP) with integrated electrochemical sensors, microfluidic channels and microneedles was demonstrated with organic compatible processes. A novel amperometric glucose sensor based on carbon nanotubes/glassy carbon working electrodes and glucose oxidase enzyme encapsulated in a sol-gel derived zirconia/nafion matrix was developed to demonstrate the biosensing....
The novel properties or the unusual combinations of properties possessed by nano-structured materials open several possibilities towards fabricating advanced nano biosensors with superior sensitivity and specificity. Single-walled carbon nantubes (SWNTs) and multi-walled carbon nanotubes (MWNTs) exhibit unique properties such as chemical stability, good mechanical properties, outstanding charge-transport...
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