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We aim to characterize tissues of skin ulcers for bacterial infection quantitatively. The echo amplitude envelope of the backscattered signals can be described by some statistics distributions in consistent with the different scattering. The basic statistics distributions (Rayleigh, K, and Rician distributions) were used to detect the difference of backscattered signals between non-infected and infected...
Cette étude propose d’évaluer la robustesse d’une méthode régularisée de correction de l’atténuation des microbulles en imagerie de contraste ultrasonore (ICU) in vivo. L’approche régularisée repose sur l’hypothèse d’une proportionnalité entre les coefficients d’atténuation et de rétrodiffusion et sur une condition limite dans une région de référence reflétant l’atténuation cumulée (AC) des microbulles...
We previously reported a noncontact ultrasound water jet indentation system for measuring and mapping tissue mechanical properties. The key idea was to utilize a water jet as an indenter as well as the coupling medium for high-frequency ultrasound. In this paper, the system was employed to assess articular cartilage degeneration, using stiffness ratio as an indicator of the mechanical properties of...
Currently, modifications of lymph node (LN) size in mice are evaluated using invasive characterization of LN cell- count and weight after dissection. This work evaluated the use of 24-MHz ultrasound to discriminate modifications of LN size in vivo. The sub-iliac LN are very small organs (long axis approximately two millimeters for adult C57BL/6 mice) situated about one millimeter beneath the skin...
Characterizing occurrence of ultrasound contrast agent (UCA) microbubble destruction is important for development of functional and therapeutic applications. Previously [Ammi, et. al., 2006], it was demonstrated that post-excitation acoustic emissions detected with passive cavitation detection (PCD) result from inertial cavitation (IC) of UCA after shell rupture. That work relied on time-consuming...
The goal of this work is to apply ultrasonic contrast techniques for noninvasive, in vivo, monitoring of Wilms' tumor angiogenesis in the mouse. Tumors were induced by renal subcapsular injection of human tumor cells in nude mice (N = 56). At 18, 21, 27 and 28 days after tumor-cell injection, contrast imaging was performed with an Acuson Sequoia (7-14 MHz, contrast pulse sequence mode). Estimates...
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