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Vibro-acoustography is an imaging method that uses the radiation force of two interfering ultrasound beams of slightly different frequency to probe an object. An image is formed using the resulting low-frequency acoustic emission from the object's vibration at the difference frequency. A previously unstudied information signal is present during vibro-acoustography, which is formed by the sum frequency...
Acoustic pressure (P) traveling in a biologic fluid or tissue generates a local change in electrical conductivity. This acoustoelectric interaction (AE) induces a voltage modulation that depends on local current, resistance, and pressure. We explore the AE signal as a way to enhance traditional electrophysiology or surface recording of neural signals. A thin stretch tube mimicking an enlarged axon...
High-frequency (i.e., > 15 MHz) ultrasound (HFU) permits fine-resolution imaging. However, the limited depth of field (DOF) and acoustic penetration depth of HFU waves limits its clinical use to the assessment of shallow diseases such as ocular or dermatological conditions. The aim of this study is to use modern annular array transducer technology and coded signals to improve DOF and penetration...
To evaluate bone strength, it is significant to measure the degree of deformation or strain of bone under a certain load. However no method has been available to non-invasively measure bone deformation. To obtain bone mechanical properties such as elasticity, viscoelasticity and plasticity, we need to externally apply a load to a bone and to accurately measure the small displacement of a specific...
Measurements from many laboratories indicate that on average the phase velocity of ultrasonic waves propagating in bone decreases with increasing frequency. This negative dispersion in bone is inconsistent with the nearly local approximation to the Kramers-Kronig relations with one subtraction that relates attenuation to dispersion. We hypothesized that observed negative dispersion in bone might result...
Identification and localization of bone surfaces in ultrasound (US) images is an essential step in US-based image guided orthopedic procedures. However, US images often depict bones poorly compared to other medical imaging modalities, such as computed tomography (CT) or magnetic resonance (MR), because of speckle, reverberation, shadowing and other artifacts. As a result, accurate, robust and automatic...
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