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Today, the diseases are being treated with less invasive and more sophisticated, technology-oriented methods. The diagnostic tools that were usually used in the hospitals have become available at our homes. Within the heart of this new generation health-care systems, CMOS technology lies with its high capability of integration, low power consumption, and low cost. Within this context, CMOS image sensors...
A novel CMOS image sensor is proposed to overcome the analog design limitations in Active Pixel Sensors — APS and large area overcome in Digital Pixel Sensors — DPS for use in bio-medical applications. The design includes a pixel level event generation mechanism by using a binary search technique. A ramp voltage generated by a combined block of 10-bit counter and DAC Digital to Analog Converter is...
High quality CMOS image sensors are of great importance for LoC — Lab-on-Chip devices based on optical measurements. The main target in these devices is to minimize the cost and area while achieving a good resolution. The performance parameters of image sensor pixels and CMOS compatible photodiodes depend on the size, type and the geometry of the photodiode layout and varies for each technology. In...
Despite the huge research effort to improve the performance of the complementary metal oxide semiconductor (CMOS) image sensors, charge-coupled devices (CCDs) still dominate the cell biology-related conventional fluorescence microscopic imaging market where low or ultra-low noise imaging is required. A detailed comparison of the sensor specifications and performance is usually not provided by the...
In biological applications and systems where even the smallest details have a meaning, CCD cameras are mostly preferred and they hold most of the market share despite their high costs. In this paper, we propose a custom-designed CMOS camera to compete with the default CCD camera of an inverted microscope for fluorescence imaging. The custom-designed camera includes a commercially available mid-performance...
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