Search results for: Taizo Uchimoto

Items from 1 to 14 out of 14 results

article

Re‐challenging chemotherapy after pembrolizumab in platinum‐refractory urothelial carcinoma

Taizo Uchimoto, Tatsuo Fukushima, Kazumasa Komura, Wataru Fukuokaya, more

Objectives To assess the real‐world clinical benefit of re‐challenging chemotherapy after pembrolizumab in patients with metastatic urothelial carcinoma (mUC), as there have been several reports suggesting that programmed cell death protein‐1/programmed death‐ligand 1inhibitors can restore platinum sensitivity. Patients and Methods Of 236 patients treated with pembrolizumab, we excluded 45 patients...

article

Risk stratification for the prediction of overall survival could assist treatment decision‐making at diagnosis of castration‐resistant prostate cancer: a multicentre collaborative study in Japan

Taizo Uchimoto, Kazumasa Komura, Wataru Fukuokaya, Takahiro Kimura, more

BJU International > 127 > 2 > 212 - 221

Objectives To assess whether a new risk stratification system according to predictors for overall survival (OS) at the diagnosis of metastatic castration‐resistant prostate cancer (mCRPC) could determine treatment outcomes and assist in treatment decision‐making. Patients and Methods Two independent clinical cohorts of patients, treated with androgen signalling inhibitors (ASIs: abiraterone and...

article

Prognostic impact of C-reactive protein-albumin ratio for the lethality in castration-resistant prostate cancer

Taizo Uchimoto, Kazumasa Komura, Yuya Fujiwara, Kenkichi Saito, more

Medical Oncology > 2020 > 37 > 1 > 1-9

This study aimed to assess the clinical value of C-reactive protein-albumin ratio (CAR) at the initiation of first-line treatment for castration-resistant prostate cancer (CRPC). We identified 221 CRPC patients treated with either androgen-signaling inhibitors (ASIs: abiraterone and enzalutamide) or docetaxel as the first-line treatment. The value of CAR was evaluated at the initiation of first-line...

article

What has changed in kidney transplantation in small islands in Japan? Experience in our center

Hajime Hirano, Ryoichi Maenosono, Tomohisa Matsunaga, Hirofumi Uehara, more

Renal Replacement Therapy > 2017 > 3 > 1 > 1-4

Background Okinoerabu Island and Tokunoshima Island lie in the sea to the south of the Japanese mainland, about 100 km north of Okinawa and about 500 km south of Kyushu. There are no facilities that specialize in kidney transplants, so the patients need to leave the island to undergo the procedure. Up to a few years ago, there were less than five kidney transplant patients on the island. We report...

article

Preoperative Measurement of the Modified Glasgow Prognostic Score Predicts Patient Survival in Non-Metastatic Renal Cell Carcinoma Prior to Nephrectomy

Takuya Tsujino, Kazumasa Komura, Tomohisa Matsunaga, Yuki Yoshikawa, more

Annals of Surgical Oncology > 2017 > 24 > 9 > 2787-2793

Purpose The modified Glasgow Prognostic Score (mGPS) by measurement of serum C-reactive protein and albumin levels has been shown to provide prognostic value in various cancer types. The purpose of this study was to evaluate whether preoperative assessment of the mGPS predicts patient survival outcome in renal cell carcinoma (RCC). Materials and Methods Clinicopathological and follow-up data in...

article

Remarkable response to fluorouracil, leucovorin, oxaliplatin, and irinotecan therapy in urothelial cancer of the renal pelvis: a case report

Takuya Tsujino, Kiyoshi Takahara, Tomohisa Matsunaga, Yuki Yoshikawa, more

Journal of Medical Case Reports > 2017 > 11 > 1 > 1-4

Background No standard chemotherapy regimen for advanced urothelial cancer has been established, except for cisplatin-based regimens. We report the case of a patient with double primary cancer, urothelial carcinoma of the upper urinary tract and colorectal cancer, who underwent oxaliplatin-based chemotherapies. Case presentation A 56-year-old Japanese man presented to our hospital with the diagnosis...

article

MP10-08 A PANEL OF MICRO-RNA SIGNATURE AS A TOOL FOR PREDICTING SURVIVAL OF PATIENTS WITH UROTHELIAL CARCINOMA OF THE BLADDER

Teruo Inamoto, Kiyoshi Takahara, Naokazu Ibuki, Tomoaki Takai, more

The Journal of Urology > 2017 > 197 > 4(S) > e111

article

MP21-05 MULTIMODAL BLADDER PRESERVATION TECHNIQUE FOR MUSCLE INVASIVE BLADDER CANCER: RESULTS FROM A PROSPECTIVE TRIAL

Teruo Inamoto, Kiyoshi Takahara, Naokazu Ibuki, Tomoaki Takai, more

The Journal of Urology > 2017 > 197 > 4(S) > e249

article

MP61-05 INTRAVESICAL INSTILLATION OF EXOGENOUS MICRORNA-145 AS A THERAPY FOR MOUSE ORTHOTOPIC HUMAN BLADDER CANCER XENOGRAFT

Teruo Inamoto, Kohei Taniguchi, Kiyoshi Takahara, Ayako Iwatsuki, more

The Journal of Urology > 2016 > 195 > 4(S) > e804-e805

article

MP7-02 THE SYSTEMIC INFLAMMATION-BASED GLASGOW PROGNOSTIC SCORE AS A POWERFUL PROGNOSTIC FACTOR IN PATIENTS WITH UPPER TRACT UROTHELIAL CARCINOMA

Teruo Inamoto, Shigeru Sakano, Tomoaki Takai, Kazumasa Komura, more

The Journal of Urology > 2015 > 193 > 4 Supplement > e64

article

Incidence of urethral stricture after bipolar transurethral resection of the prostate using TURis: results from a randomised trial

Kazumasa Komura, Teruo Inamoto, Tomoaki Takai, Taizo Uchimoto, more

BJU International > 115 > 4 > 644 - 652

ObjectivesTo assess whether bipolar transurethral resection of the prostate (B‐TURP) using the TURis^® system has a similar level of efficacy and safety to that of the traditional monopolar transurethral resection of the prostate (M‐TURP), and to evaluate the impact of the TURis system on postoperative urethral stricture rates over a 36‐month follow‐up period. Patients and MethodsA total of 136 patients...

article

Novel Bladder Preservation Therapy with Osaka Medical College Regimen

Haruhito Azuma, Teruo Inamoto, Kiyoshi Takahara, Hayahito Nomi, more

The Journal of Urology > 2015 > 193 > 2 > 443-450

We investigated the effect of balloon occluded arterial infusion of an anticancer agent (cisplatin/gemcitabine), used concomitantly with hemodialysis, which delivers an extremely high concentration of anticancer agent to the tumor site without systemic adverse effects, along with concurrent radiation (referred to as the Osaka Medical College regimen) in patients with advanced bladder cancer.A total...

article

Could Transurethral Resection of the Prostate Using the TURis System Take Over Conventional Monopolar Transurethral Resection of the Prostate? A Randomized Controlled Trial and Midterm Results

Kazumasa Komura, Teruo Inamoto, Tomoaki Takai, Taizo Uchimoto, more

Urology > 2014 > 84 > 2 > 405-411

To assess whether bipolar transurethral resection of the prostate using the TURis (Olympus, Tokyo, Japan) system demonstrates comparable efficacy and safety reporting 36 months of follow-up findings.The trial was registered at University hospital Medical Information Network Clinical Trials Registry in Japan (trial number UMIN 000010801). Patients were randomly selected to undergo transurethral resection...

article

Single session of high-intensity focused ultrasound for localized prostate cancer: treatment outcomes and potential effect as a primary therapy

Kazumasa Komura, Teruo Inamoto, Tomoaki Takai, Taizo Uchimoto, more

World Journal of Urology > 2014 > 32 > 5 > 1339-1345

Purpose To investigate the treatment outcomes of a single-session high-intensity focused ultrasound (HIFU) using the Sonablate^® for patients with localized prostate cancer. Methods Biochemical failure was defined according to the Stuttgart definition [a rise of 1.2 ng/ml or more above the nadir prostate-specific antigen (PSA)] and the Phoenix definition (a rise of 2 ng/ml or more above the nadir...

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ABIRATERONE (2)
ENZALUTAMIDE (2)
UROTHELIAL CARCINOMA (2)
#PCSM (1)
#PROSTATECANCER (1)
#UROONC (1)
ALKALINE PHOSPHATASE (1)
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KIDNEY TRANSPLANTATION (1)
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OUTCOME (1)
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SINGLE-SESSION TREATMENT (1)
TRANSURETHRAL RESECTION OF THE PROSTATE (1)
UPPER TRACT UROTHELIAL CARCINOMA (1)
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