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Acute kidney injury causes great morbidity and mortality in both the community and hospital settings. Understanding the etiological factors and the pathophysiological principles resulting in acute kidney injury is essential in prompting appropriate therapies. Recently hyperuricemia has been recognized as a potentially modifiable risk factor for acute kidney injury, including that associated with cardiovascular...
Microsystem design includes different domains (e.g. microelectronics, micro mechanics, etc.) and is characterized by multidisciplinarity. Growing demands and complexity result in new challenges for computer-aided microsystem design. Developments from SMEs (small and medium sized enterprises) are often heterogeneous modular-based microsystems associated with collaborations of several companies. The...
System Integration using 3D technology is a very promising way to cope with current and future requirements for electronic systems. Since the pure shrinking of devices (known as “More Moore”) will come to an end due to physical and economic restrictions, the integration of systems (e.g. by stacking dies, or by adding sensor functions) shows a way to maintain the growth in complexity as well as in...
In recent years 3D IC design and manufacturing is continuously emerging. Along with the variety of possibilities on how to vertically integrate two or more dies, many aspects including cost, design and choice of technology must be considered. Therefore a design methodology and software implementation is presented in this paper which makes use of the mutual dependency of design and process technology...
Developing 3D systems is a highly complex procedure. Next to a huge variation of possibilities on how to vertically integrate two or more dies, a lot of aspects regarding cost, design and application specific selection of technology have to be considered. Therefore a design model, considering the mutual influence of design and process technology during the integration flow development and a data management...
Product engineering of micro and nano technology (MNT) devices differs substantially from product engineering in more traditional industries. The general approach is mostly bottom up, as it centers around the available fabrication techniques. The strong emphasis on manufacturing technology in this area leads to a large number of application specific fabrication processes. In the first part of this...
In this paper an approach for fabrication process design automation is presented that is backed up by a comprehensive process data management system. The synthesis procedure is roughly based on an approach originally developed at the University of Michigan. It starts with a two-dimensional cross-section representation of the intended MEMS structure that is analysed to identify typical process features...
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