Witold X. Chmielewski

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How high‐dose alcohol intoxication affects the interplay of automatic and controlled processes

Witold X. Chmielewski, Nicolas Zink, Keluf Ylva Chmielewski, Christian Beste, more

Binge drinking is an increasingly prevalent pattern of alcohol consumption that impairs top‐down cognitive control to a much stronger degree than automatic response generation. Even though an imbalance of those two antagonistic processes fosters the development and maintenance of alcohol use disorders (AUDs), it has never been directly investigated how binge drinking affects the interaction of those...

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How the depth of processing modulates emotional interference – evidence from EEG and pupil diameter data

Marie Luise Schreiter, Witold X. Chmielewski, Moritz Mückschel, Tjalf Ziemssen, more

Cognitive, Affective, & Behavioral Neuroscience > 2019 > 19 > 5 > 1231-1246

The ability to process emotionally conflicting information is an important requirement for emotional self-control. While it seems obvious that the impact of interfering emotional information critically depends on how deeply this interfering information is processed, it is still unknown what cognitive subprocesses are most affected by manipulating the depth of processing of emotionally interfering...

article

How socioemotional setting modulates late-stage conflict resolution processes in the lateral prefrontal cortex

Marie Luise Schreiter, Witold X. Chmielewski, Christian Beste

Cognitive, Affective, & Behavioral Neuroscience > 2018 > 18 > 3 > 521-535

The goal-directed control of behaviour critically depends on emotional regulation and constitutes the basis of mental well-being and social interactions. Within a socioemotional setting, it is necessary to prioritize effectively the relevant emotional information over interfering irrelevant emotional information to orchestrate cognitive resources and achieve appropriate behavior. Currently, it is...

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Response selection codes in neurophysiological data predict conjoint effects of controlled and automatic processes during response inhibition

Witold X. Chmielewski, Moritz Mückschel, Christian Beste

Human Brain Mapping > 39 > 4 > 1839 - 1849

The inhibition of prepotent responses is a requirement for goal‐directed behavior and several factors determine corresponding successful response inhibition processes. One factor relates to the degree of automaticity of pre‐potent response tendencies and another factor relates to the degree of cognitive control that is exerted during response inhibition. However, both factors can conjointly modulate...

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Effects of multisensory stimuli on inhibitory control in adolescent ADHD: It is the content of information that matters

Witold X. Chmielewski, Angela Tiedt, Annet Bluschke, Gabriel Dippel, more

NeuroImage: Clinical > 2018 > 19 > C > 527-537

Even though deficits in inhibitory control and conflict monitoring are well-known in ADHD, factors that further modulate these functions remain to be elucidated. One factor that may be of considerable importance is how inhibitory control is modulated by multisensory information processing. We examined the influence of concurrent auditory conflicting or redundant information on visually triggered response...

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Testing interactive effects of automatic and conflict control processes during response inhibition – A system neurophysiological study

Witold X. Chmielewski, Christian Beste

NeuroImage > 2017 > 146 > C > 1149-1156

In everyday life successful acting often requires to inhibit automatic responses that might not be appropriate in the current situation. These response inhibition processes have been shown to become aggravated with increasing automaticity of pre-potent response tendencies. Likewise, it has been shown that inhibitory processes are complicated by a concurrent engagement in additional cognitive control...

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The norepinephrine system affects specific neurophysiological subprocesses in the modulation of inhibitory control by working memory demands

Witold X. Chmielewski, Moritz Mückschel, Tjalf Ziemssen, Christian Beste

Human Brain Mapping > 38 > 1 > 68 - 81

Inhibitory control processes are known to be modulated by working memory demands. However, the neurobiological mechanisms behind these modulations are inconclusive. One important system to consider in this regard is the locus coeruleus (LC) norepinephrine (NE) system. In the current study the role of the LC‐NE system by means of pupil diameter recordings that are integrated with neurophysiological...

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Paradox effects of binge drinking on response inhibition processes depending on mental workload

Ann-Kathrin Stock, Lea Riegler, Witold X. Chmielewski, Christian Beste

Archives of Toxicology > 2016 > 90 > 6 > 1429-1436

Binge drinking is an increasing problem in Western societies, but we are still only beginning to unravel the effects of binge drinking on a cognitive level. While common sense suggests that all cognitive functions are compromised during high-dose ethanol intoxication, several studies suggest that the effects might instead be rather specific. Moreover, some results suggest that the degrees of automaticity...

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Concurrent information affects response inhibition processes via the modulation of theta oscillations in cognitive control networks

Witold X. Chmielewski, Moritz Mückschel, Gabriel Dippel, Christian Beste

Brain Structure and Function > 2016 > 221 > 8 > 3949-3961

Inhibiting responses is a challenge, where the outcome (partly) depends on the situational context. In everyday situations, response inhibition performance might be altered when irrelevant input is presented simultaneously with the information relevant for response inhibition. More specifically, irrelevant concurrent information may either brace or interfere with response-relevant information, depending...

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Predictability and context determine differences in conflict monitoring between adolescence and adulthood

Witold X. Chmielewski, Veit Roessner, Christian Beste

Behavioural Brain Research > 2015 > 292 > C > 10-18

The ability to link contextual information to actions is an important aspect of conflict monitoring and response selection. These mechanisms depend on medial prefrontal networks. Although these areas undergo a protracted development from adolescence to adulthood, it has remained elusive how the influence of contextual information on conflict monitoring is modulated between adolescence and adulthood...

article

The impact of mental workload on inhibitory control subprocesses

Witold X. Chmielewski, Moritz Mückschel, Ann-Kathrin Stock, Christian Beste

NeuroImage > 2015 > 112 > C > 96-104

The inhibition of inappropriate responses is a function known to rely on prefrontal cortex (PFC) functioning. Similarly, working memory processes are known to rely on the PFC. Even though these processes are usually closely intertwined and the functional neuroanatomy underlying these processes is largely overlapping, the influence of working memory load on inhibitory control process has remained largely...

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Action control processes in autism spectrum disorder – Insights from a neurobiological and neuroanatomical perspective

Witold X. Chmielewski, Christian Beste

Progress in Neurobiology > 2015 > 124 > Complete > 49-83

Autism spectrum disorders (ASDs) encompass a range of syndromes that are characterized by social interaction impairments, verbal and nonverbal communication difficulties, and stereotypic or repetitive behaviours. Although there has been considerable progress in understanding the mechanisms underlying the changes in the ‘social’ and ‘communicative’ aspects of ASD, the neurofunctional architecture of...

article

Expectancy effects during response selection modulate attentional selection and inhibitory control networks

Witold X. Chmielewski, Moritz Mückschel, Veit Roessner, Christian Beste

Behavioural Brain Research > 2014 > 274 > C > 53-61

Choosing the correct response from a subset of alternatives is a fundamental problem and particularly demanding where conflicting response tendencies are evident. One phenomenon in this context is the congruency sequence-(Gratton effect), for which different theoretical explanations have been put forward. A critical aspect that differs between these explanations is the expectancy of what will happen...

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Search results for: Witold X. Chmielewski

How high‐dose alcohol intoxication affects the interplay of automatic and controlled processes

How the depth of processing modulates emotional interference – evidence from EEG and pupil diameter data

How socioemotional setting modulates late-stage conflict resolution processes in the lateral prefrontal cortex

Response selection codes in neurophysiological data predict conjoint effects of controlled and automatic processes during response inhibition

Effects of multisensory stimuli on inhibitory control in adolescent ADHD: It is the content of information that matters

Testing interactive effects of automatic and conflict control processes during response inhibition – A system neurophysiological study

The norepinephrine system affects specific neurophysiological subprocesses in the modulation of inhibitory control by working memory demands

Paradox effects of binge drinking on response inhibition processes depending on mental workload

Concurrent information affects response inhibition processes via the modulation of theta oscillations in cognitive control networks

Predictability and context determine differences in conflict monitoring between adolescence and adulthood

The impact of mental workload on inhibitory control subprocesses

Action control processes in autism spectrum disorder – Insights from a neurobiological and neuroanatomical perspective

Expectancy effects during response selection modulate attentional selection and inhibitory control networks

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