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Determination of analytes (e.g. glucose) in complex samples (e.g. blood) is one of the challenging task of recent bio-analytical chemistry. For this purpose various kinds of sensors are applied, however, the simplest and cheapest sensors, and thus the most widely exploited, are electrochemical enzymatic biosensors. However, these sensors still has number of limitations to overcome in order to demonstrate...
Monitoring of metabolic compounds in cell cultures can provide real-time information of cell line status. This is particularly important in those lines not fully known, as the case of embryonic and mesenchymal cells. On the other hand, such approach can pave the way to fully automated systems for growing cell cultures, when integrated in Petri dishes. To date, the main efforts emphasize the monitoring...
The present application is based on the use of carbon nanotubes (CNTs) for biomolecular analysis using electrochemiluminescence (ECL) detection technique [1]-[9]. For this purpose we have grown self standing blocks of multi-wall CNTs (MWCNTs). The blocks were subsequently back-contacted and encapsulated into epoxy resin for their use as voltammetric electrodes. A ruthenium-complex solution has been...
An evaluation of concepts, terms and methodology used at electrochemical nucleic acids-based biosensors is given together with the demonstration of effectiveness of the application of selected nanomaterials at the construction of carbon paste-based disposable electrochemical NA biosensors.
A nanobioelectronic system-on-package (SOP) with integrated electrochemical sensors, microfluidic channels and microneedles was demonstrated with organic compatible processes. A novel amperometric glucose sensor based on carbon nanotubes/glassy carbon working electrodes and glucose oxidase enzyme encapsulated in a sol-gel derived zirconia/nafion matrix was developed to demonstrate the biosensing....
A novel disposable lactate biosensor was reported, which can measure the lactate in whole blood and other bio-fluids rapidly, accurately, expediently and directly. The biosensor was based on two kinds of electron mediator, the ferricyanide and the modified carbon nanotubes (CNT). Lactate oxidase (LOD) was coated on the electrodes. The sensor was fabricated by screen-printed techniques, the sample...
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