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The HLA‐DPB1 locus has been demonstrated to have a significant role on patients' outcome after allogeneic HSCT, and the so‐called T‐cell epitope (TCE) algorithm has been incorporated in international guidelines for the selection of unrelated donors. The purpose of the present study is to measure, through a national survey conducted on behalf of the Associazione Italiana di Immunogenetica e Biologia...
In this report we describe the characterization of a novel null HLA‐DQB1 allele, detected by polymerase chain reaction‐sequence‐based typing but not by next‐generation sequencing (NGS). The new allele, HLA‐DQB1*06:379N, was discovered in an Italian patient with acute myeloid leukemia and also in one of her healthy siblings. The new allele is largely homologous to DQB1*06:02:01:01 with a T deletion...
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