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Extensive research has shown that aberrant expression of microRNAs (miRNAs) plays an important role in innate and adaptive immune responses. The rs2910164 polymorphism has been identified as a functional variant, which affects the transcription and expression level of miR‐146a and, thereby, contributes to the pathogenesis of several inflammatory and autoimmune diseases. To investigate whether the...
Background Adolescent obesity is associated with an increased risk of adult obesity and subsequent cardiovascular diseases. The present study aimed to assess the effect of weight loss after 6‐month lifestyle intervention in obese adolescents on biomarkers of endothelial activation and fibrinolytic system.
Methods Eighty‐five obese adolescents aged 10 to 16 years were assigned to a 6‐month lifestyle...
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