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Background
The immunopathology of autoimmune seronegative myasthenia gravis (SN MG) is poorly understood. Our objective was to determine immune profiles associated with a diagnosis of SN MG.
Methods
We performed high‐dimensional flow cytometry on blood samples from SN MG patients (N = 68), healthy controls (N = 46), and acetylcholine receptor antibody (AChR+) MG patients (N = 27). We compared 12...
IntroductionWe evaluated the response to immunosuppression in a case of 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase (HMGCR)‐autoantibody myopathy.
MethodsT‐ and B‐cell subsets were determined by flow cytometry pre‐ and posttherapy.
ResultsBaseline immune profiling demonstrated strikingly elevated T‐follicular helper (Tfh) cells and plasmablasts. Immunosuppression resulted in clinical improvement...
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