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We identified CD8+ CD122+ regulatory T cells (CD8+ CD122+Treg cells) and reported their importance in maintaining immune homeostasis. The absence of CD8+ CD122+Treg cells has been shown to lead to severe systemic autoimmunity in several mouse models, including inflammatory bowel diseases and experimental autoimmune encephalomyelitis. The T‐cell receptors (TCRs) expressed on CD8+ CD122+Treg cells recognize...
The aim of this study was to investigate changes in CD4+CD25+FOXP3+ regulatory T cells (Tregs) throughout the clinical course of Kawasaki disease (KD) and correlations with response to intravenous immunoglobulin (IVIg) therapy. Participants comprised 18 patients who fulfilled the diagnostic criteria for KD and 20 healthy subjects. Expressions of CD25 and FOXP3 among all CD4+ T cells in peripheral...
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