Search results for: Rong‐sheng Li

Items from 1 to 10 out of 10 results

article

Enzyme‐Activatable Polypeptide for Plasma Membrane Disruption and Antitumor Immunity Elicitation

Jiahui Liu, Rong Sheng Li, Lei Zhang, Jie Wang, more

Small > 19 > 24 > n/a - n/a

Enzyme‐instructed self‐assembly of bioactive molecules into nanobundles inside cells is conceived to potentially disrupt plasma membrane and subcellular structure. Herein, an alkaline phosphatase (ALP)‐activatable hybrid of ICG‐CF₄KY^p is facilely synthesized by conjugating photosensitizer indocyanine green (ICG) with CF₄KY^p peptide via classical Michael addition reaction. ALP‐induced dephosphorylation...

article

Simultaneous determination of eight analytes of Fuzheng Huayu recipe in beagle dog plasma by UHPLC–Q/exactive Orbitrap HRMS and its application to toxicokinetics

Yu‐Lin Wang, Ming‐jv Yang, Rong‐sheng Li, Ye‐qing Hu, more

Biomedical Chromatography > 36 > 4 > n/a - n/a

Fuzheng Huayu recipe (FZHY) is a Chinese patent medicine for the treatment of liver fibrosis. This study aimed to investigate the toxicokinetics of FZHY in beagle dogs after oral administration. Blood samples were collected on days 1, 15 and 28 after oral gavage of FZHY dosages of 400 or 1,200 mg/kg body weight once a day. A UHPLC–Q‐Orbitrap method was developed and validated to simultaneously determine...

article

Synthesis and anti‐hepatocellular carcinoma activity in vitro of cyclic peptide GG‐8‐6 analogues

Xiao‐Zhi Hu, Rong‐Sheng Li, Jie‐Tao Chen, Qing Mu

Journal of Heterocyclic Chemistry > 59 > 3 > 507 - 517

Our previous study reported a cyclic peptide, GG‐8‐6, possessing effective activity against hepatocellular carcinoma both in vitro and in vivo. In order to seek out better analogues in synthetic yield or bioactivity, we synthesized 15 cyclopeptide GG‐8‐6 analogues. Their purities were detected by HPLC, and their structures were characterized by HR‐QTOF‐MS, ¹H and ¹³C NMR together with X‐ray crystal...

article

Identification and characterization of a novel esterase from Thauera sp.

Niu Yu, Jin‐chang Yang, Guang‐tian Yin, Rong‐sheng Li, more

Biotechnology and Applied Biochemistry > 65 > 5 > 748 - 755

A novel esterase gene TLip was identified from the strain Thauera sp. and expressed at high levels in Escherichia coli. The TLip protein shared the highest identity (48%) to esterase TesA from Pseudomonas aeruginosa when compared to enzymes with reported properties. Phylogenetic analysis showed that TLip belongs to the GDSL family of bacterial lipolytic enzymes. TLip was an alkaline esterase with...

article

Highly selective detection of phosphate ion based on a single-layered graphene quantum dots-Al3+ strategy

Bin Bin Chen, Rong Sheng Li, Meng Li Liu, Hong Yan Zou, more

Talanta > 2018 > 178 > C > 172-177

Determination of phosphate ion (PO₄^3-) is important in biomedical and environmental arrays because its controlling concentrations are associated with different pathologies or the quality of water. Herein, we report a new type of photoluminescence (PL) probe for highly selective detection of PO₄^3- based on a single-layered graphene quantum dots chelating with aluminium ions (s-GQDs-Al³⁺) system. The...

article

Highly fluorescent carbon dots as selective and visual probes for sensing copper ions in living cells via an electron transfer process

Jian Wang, Rong Sheng Li, Hong Zhi Zhang, Ni Wang, more

Biosensors and Bioelectronics > 2017 > 97 > C > 157-163

As an integral part of many important enzymes, Cu²⁺ is involved in a number of vital biological processes, which is linked to the oxidative damage and environmental contamination when Cu²⁺ is excessive. In this work, Cu²⁺ can be captured by the amino groups of carbon dots (CDs) to form complexes, resulting in a strong fluorescence quenching of CDs via a nonradiative electron transfer process, which...

article

Genetic diversity and structure among natural populations of Sindora glabra in Hainan Island, China as revealed by ISSR markers

Jin-chang Yang, Qiong-Qiong Li, Niu Yu, Guang-tian Yin, more

Biochemical Systematics and Ecology > 2016 > 69 > C > 145-151

Sindora glabra, one of the second-class national protective plants in China, has important ecological and commercial values. To understand the genetic diversity and structure of S. glabra, eleven natural populations from four areas of Hainan Island in China were analyzed by inter-simple sequence repeat (ISSR) markers. Thirteen primers were screened out and used to amplify 157 DNA samples. A total...

article

Localized surface plasmon resonance of gold nanorods and assemblies in the view of biomedical analysis

Jian Wang, Hong Zhi Zhang, Rong Sheng Li, Cheng Zhi Huang

TrAC Trends in Analytical Chemistry > 2016 > 80 > C > 429-443

As a new class of anisotropic nanomaterial, gold nanorods (AuNRs) have received much attention due to their unique optical and photothermal properties. Much different from the spherical nanoparticles, AuNRs display two characteristic transverse and longitudinal surface plasmon absorption bands. This absorbed light is able to act as the energy acceptors in the fluorescence resonance energy transfer...

article

Shoot drying and its cause in Calamus simplicifolius at Nanmeiling, Hainan, China

Rong-sheng Li, Guang-tian Yin, Jin-chang Yang, Wen-tao Zou, more

Journal of Forestry Research > 2011 > 22 > 4 > 681-684

Many stems are subject to shoot drying in the plantations of Calamus simplicifolius Wei at the Nanmeiling Base of the Forestry Bureau of Baisha County, Hainan Province. As a palm, stems of C. simplicifolius stop growing and later die if the shoots are dry. Generally, shoot drying means reduced cane production and reduced profit for a rattan plantation. We aimed to quantify the incidence of shoot drying...

article

Rattan sector in Hainan Island, China: a case study

Rong-sheng Li, Guang-tian Yin, Jin-chang Yang, Wen-tao Zou

Journal of Forestry Research > 2007 > 18 > 2 > 153-156

Hainan Island is the biggest supplier of domestic rattan canes in China and is considered the best area to develop rattan plantation in large-scale. This paper discusses the rattan production in Hainan Island on the basis of comprehensively collected information on rattan through interviewing with farmers, middle man, manufacture and official, on-site observation and literatures. The stock of available...

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