Search results for: Sara Quercia

Items from 1 to 11 out of 11 results

article

Characterization of the human DNA gut virome across populations with different subsistence strategies and geographical origin

Simone Rampelli, Silvia Turroni, Stephanie L. Schnorr, Matteo Soverini, more

Environmental Microbiology > 19 > 11 > 4728 - 4735

It is a matter of fact that the human gut microbiome also includes a non‐bacterial fraction represented by eukaryotic cells and viruses. To further explore the gut microbiome variation in human populations, here we characterized the human DNA viral community from publicly available gut metagenome data sets from human populations with different geographical origin and lifestyle. In particular, such...

article

Trastuzumab resumption after extremely severe cardiotoxicity in metastatic breast cancer patient: a case report

Santino Minichillo, Ilaria Gallelli, Elena Barbieri, Marta Cubelli, more

BMC Cancer > 2017 > 17 > 1 > 1-5

Background Trastuzumab-related cardiotoxicity has been reported in patients receiving trastuzumab concurrently with other agents, especially with anthracyclines. Cardiac function damage is generally rare, precox and mild with trastuzumab alone. Case presentation We report the case of a 49 year-old woman affected by metastatic breast cancer who developed trastuzumab-related cardiogenic shock due...

article

Gut microbiome response to short‐term dietary interventions in reactive hypoglycemia subjects

Sara Quercia, Silvia Turroni, Jessica Fiori, Matteo Soverini, more

Diabetes/Metabolism Research and Reviews > 33 > 8 > n/a - n/a

Background Reactive hypoglycemia is a metabolic disorder that provokes severe hypoglycemic episodes after meals. Over recent years, the gut microbiota has been recognized as potential target for the control of metabolic diseases, and the possibility to correct gut microbiota dysbioses through diet, favouring the recovery of metabolic homeostasis, has been considered. Methods We investigate the...

article

The gut microbiota of centenarians: Signatures of longevity in the gut microbiota profile

Elena Biagi, Simone Rampelli, Silvia Turroni, Sara Quercia, more

Mechanisms of Ageing and Development > 2017 > 165 > PB > 180-184

The changing physiology and lifestyle of elderly people affect the gut microbiota composition, the changes of which can, in turn, affect the health maintenance of the ageing host. In a co-evolutionary vision of the relationship between gut microbiota and ageing as an adaptive process of the human superorganism, long-living individuals who get to “successfully” age might be the ones whose microbiota...

article

Temporal dynamics of the gut microbiota in people sharing a confined environment, a 520-day ground-based space simulation, MARS500

Silvia Turroni, Simone Rampelli, Elena Biagi, Clarissa Consolandi, more

Microbiome > 2017 > 5 > 1 > 1-11

Background The intestinal microbial communities and their temporal dynamics are gaining increasing interest due to the significant implications for human health. Recent studies have shown the dynamic behavior of the gut microbiota in free-living, healthy persons. To date, it is not known whether these dynamics are applicable during prolonged life sharing in a confined and controlled environment. ...

article

Gut Microbiota and Extreme Longevity

Elena Biagi, Claudio Franceschi, Simone Rampelli, Marco Severgnini, more

Current Biology > 2016 > 26 > 11 > 1480-1485

The study of the extreme limits of human lifespan may allow a better understanding of how human beings can escape, delay, or survive the most frequent age-related causes of morbidity, a peculiarity shown by long-living individuals. Longevity is a complex trait in which genetics, environment, and stochasticity concur to determine the chance to reach 100 or more years of age [1]. Because of its impact...

article

ViromeScan: a new tool for metagenomic viral community profiling

Simone Rampelli, Matteo Soverini, Silvia Turroni, Sara Quercia, more

BMC Genomics > 2016 > 17 > 1 > 1-9

Background Bioinformatics tools available for metagenomic sequencing analysis are principally devoted to the identification of microorganisms populating an ecological niche, but they usually do not consider viruses. Only some software have been designed to profile the viral sequences, however they are not efficient in the characterization of viruses in the context of complex communities, like the...

article

Repolarization effects of multiple-cycle chemotherapy and predictors of QTc prolongation: a prospective female cohort study on >2000 ECGs

Igor Diemberger, Giulia Massaro, Marta Cubelli, Daniela Rubino, more

European Journal of Clinical Pharmacology > 2015 > 71 > 8 > 1001-1009

Purpose Oncological patients are at increasing risk of QT prolongation, a risk factor for ventricular arrhythmia. We assessed impact and risk factors for corrected QT (QTc) prolongation during multiple-cycle chemotherapy. Methods We enrolled 100 outpatients initiating chemotherapy in a university center specializing in female cancer. Clinical, drug, laboratory, and 12-lead ECG data collection at...

article

Bifidobacterium animalis ssp. lactis BI07 modulates the tumor necrosis factor alpha‐dependent imbalances of the enterocyte‐associated intestinal microbiota fraction

Manuela Centanni, Silvia Turroni, Simone Rampelli, Elena Biagi, more

FEMS Microbiology Letters > 357 > 2 > 157 - 163

Using a previously developed in vitro model to characterize the enterocyte‐adherent microbiota fraction, we explored the potential of the probiotic strain Bifidobacterium animalis ssp. lactis BI07 to modulate the inflammation‐dependent dysbioses of the enterocyte‐adherent microbiota from 12 healthy human donors. According to our findings, B. animalis ssp. lactis BI07 is effective in limiting the increase...

article

Explorative Study on the Predictive and Prognostic Value of Early Complete Metabolic Response By FDG-PET–CT During Neoadjuvant Chemotherapy in Patients With Advanced Ovarian Cancer

Andrea Angelo Martoni, Marta Rosati, Claudio Zamagni, Pierandrea De Jaco, more

Clinical Ovarian and Other Gynecologic Cancer > 2012 > 5 > 1 > 2-9

Early complete metabolic response (e-CMR) by fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) during neoadjuvant chemotherapy (NACT) in advanced ovarian cancer (AOC) could have predictive and prognostic value. The present explorative study prospectively investigated changes of dual-time FDG-PET, at baseline and after 3 cycles of NACT in patients who were not candidates for upfront...

article

Early ¹⁸F‐2‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography may identify a subset of patients with estrogen receptor‐positive breast cancer who will not respond optimally to preoperative chemotherapy

Andrea A. Martoni, Claudio Zamagni, Sara Quercia, Marta Rosati, more

Cancer > 116 > 4 > 805 - 813

BACKGROUND:A pathologic complete response (pCR) and minimal residual disease (pMRD) after preoperative chemotherapy (PCT) for early stage or locally advanced breast cancer (BC) correlates with a good prognosis. METHODS:Patients who received from 6 to 8 cycles of PCT for BC were monitored by ¹⁸F‐2‐fluoro‐2‐deoxy‐D‐glucose positron emission tomography (¹⁸F‐FDG‐PET), and the maximal standardized uptake...

Filter options

Publication date

Set your own date range

INFONA - science communication portal

Search results for: Sara Quercia

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options