The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The 8-oxoguanine DNA glycosylase-1 (OGG1) is one of the first lines of defense against 8-oxodg mutagenicity. The mutant hOGG1-Cys326 might be susceptible to a decrease in the repair function for oxidative DNA damage, which leads to higher oxidative DNA damage accumulation with excess oxidative stress. The purpose of this study was to investigate the effects of hOGG1 Ser326Cys polymorphisms on oxidative...