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This paper presents an approach for main parameters uniformity improvement from channel to channel in integrated circuit dedicated to multi-point neurobiological recordings. We show that if the conditioning channel size and power consumption are very limited, additional correction circuits are necessary to key parameters spread lowering. The method has been implemented in a 64-channel circuit fabricated...
We report on design of the 100 channel integrated circuit (10×10 pixel matrix) destined to complex neurobiology experiments. The chip is dedicated to both recording and stimulating neural activity and its predominant attributes comes from its individual digital control of both blocks and allocation of both in each of the pixel. Additionally, the integrated circuit is composed of RAM, ADC, bandgap...
In this paper we present a measurement system for in vivo multichannel recordings of the electrophysiological activity of brain tissue. The system consists of penetrating Microelectrode Array (MEA), three versions of a Conditioning Module each equipped with different Application Specific Integrated Circuits (ASIC), Digitizer and PC Application for recorded data presentation and storage. The MEA consists...
For many years hybrid pixel detectors working in the single photon counting mode have been used not only in high energy physics experiments but also for X-ray imaging applications. In these detectors each pixel has its independent electronic readout channel for photon by photon signal processing, what provides better image quality and possibility of counting photons only within a given energy window...
The article describes a System on Chip (SoC) for multi-channel wireless recording of nerve tissue electrical activity. Specificity of neural signals, the method of registration by using microelectrode arrays and requirements for the SoC are presented. Eventually, individual elements of the system such as conditioning module, analogue multiplexer, A/D converter, radio transmitter and system controller...
We present a measurement system for 256-channel in vitro recordings of brain tissue electrophysiological activity. The system consists of: brain tissue life support system, Microelectrode Array (MEA), 4 Application Specific Integrated Circuits (ASIC's) for signals conditioning, Digitizer and PC Application for measurement, data presentation and storage. The life support system keeps brain tissue samples...
We present a complete reconfigurable measurement system for 256-channel in vitro recordings and electrical stimulation of brain tissue electrophysiological activity. The system is built of: brain tissue life support system, Microelectrode Array (MEA), 4 multichannel integrated electronic circuits for signals conditioning and electrical stimulation, Digitizer and PC Application for measurement, data...
In this paper we present a measurement system for multichannel recordings of the electrophysiological activity of brain tissue in vivo. The system consists of: penetrating Microelectrode Array (MEA), three versions of a Conditioning Module each equipped with different Application Specific Integrated Circuits (ASIC's), Digitizer and PC Application for recorded data presentation and storage. The MEA...
This paper presents the design methods that allow to drastically limit an area of a recording channel in multichannel integrated circuits dedicated to neurobiology experiments. The techniques that are presented in this paper allow to apply them in a 3D pixel multichannel integrated systems where area limitations are very strict. Furthermore, these allow one to minimize main problems e\ xisting in...
Our report is on the simulation results and the design of the integrated circuit dedicated for inductive powering of a neural recording system on a chip. Four different voltage rectifiers were considered. designed to compare their power efficiency, drop out voltages, and ability to work in a megahertz range. Each of the full bridge rectifiers is equipped with voltage clamps to prevent it from the...
We present two different approaches to the multichannel recording ASICs dedicated for neurobiology experiments. The ASICs are processed in 180nm CMOS technology and occupy the same silicon area of 5×2.3 mm2. Presented integrated circuits include 64 recording channels and have a possibility to tune their low and high cut-off frequencies. Each recording channel consumes about 200 μW of power and is...
We present the design and measurement results of the multichannel ASIC dedicated for neurobiology experiments. Chip is fabricated in CMOS 180nm technology and comprises 64 channels. A single readout channel is able to record both neural spikes and LFP (Local Field Potential) signals. Each channel is equipped with digital registers responsible for controlling its voltage gain, low and high cut-off...
We present the architecture and preliminary measurements of an ASIC for neural signal recording. The chip consists of 64 analogue channels followed by the analogue multiplexer and it is fabricated in the 180 nm CMOS technology. It consumes 220 µW per channel from ±0.9 V power supply and occupies 13 mm2 area. User is capable to modify frequency bandwidth in the 1 Hz – 60 Hz range for low cut-off frequency...
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