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From the efforts of a number of Canadian institutions and private industry collaborations, direct production of 99mTc using medical cyclotrons has recently been advanced from a 1970's academic exercise to a commercial, economically viable solution for regional production. Using GE PETtrace 880 machines our team has established preliminary saturated yields of 2.7 GBq/μA, translating to approximately...
A derivative of auranofin, a drug used in the treatment of rheumatoid arthritis, was synthesised and examined by NMR spectroscopy and X-ray crystallography. The derivative, which contains a trisimidazole phosphine, was designed to complex hard metals in addition to binding to the gold(I) centre.
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