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Cancer treatment with Doxorubicin (DOX) is limited due its dose-dependent cardiotoxicity, mainly related to the oxidative stress production. In experimental models of DOX treatment exercise can be used as a beneficial adjuvant therapy. This work aimed to investigate the effects of exercise during pregnancy on DOX-induced cardiotoxicity in cardiomyocytes of progeny, examining the possible intergenerational...
Pilot-scale pretreatments, namely steam explosion (SE) and diluted sulfuric acid (SA), of sugarcane bagasse followed by alkaline delignification (SED and SAD) were explored. Most of the pentosan (97% and 93%), and the lignin content were solubilized during pretreatment and delignification process for SE and SA, respectively. SE demanded 50% more NaOH in the delignification step than SA, due to ion...
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