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This paper reports an innovative approach for the manipulation of micro-particles utilizing optically-induced dielectrophoresis (ODEP), which was generated by a flexible polymer-based substrate for biomedical applications. The ODEP platform fabricated on a thin-film polymer-based substrate has been reported as a promising technique for particle/cell manipulation. Without using sophisticate and high-temperature...
This paper briefly demonstrates three kinds of microfluidic modules by using a polymer-based optically-induced dielectrophoresis (ODEP) platform. Polymer materials with excellent optoelectronic efficiency can be mass-produced at room temperature using a spin-coating process. This approach can easily facilitate the mass-fabrication process of the ODEP chip. The first function presented in this platform...
Optoelectronic tweezers (OET) using ODEP forces were first demonstrated. It is now feasible to fabricate ODEP devices on flexible plastics. It is envisioned that the ODEP platform will become a promising tool for future biomedical applications. These newly developed ODEP devices are extremely useful for investigations at the single cell level. Several interesting examples using an ODEP platform have...
A new microfluidic reaction system capable of mixing, sample transportation and reaction is developed for synthesis of alloy magnetic nanoparticles. It allows for a rapid and cost-effective approach to accelerate the synthesis of the nanoparticles. The system integrated a micro-mixer/micro-pump, a micro-condenser, micro-valves, micro-heaters, and a micro temperature sensor to form a new microfluidic...
In the study, we report a microfluidic-based dispenser fabricated by standard soft lithography of PDMS (polydimethylsiloxane) for sub-microliter range precise pipetting. The key feature of the microfluidic-based dispenser is the incorporation of a pressure-generating unit providing the driving force for precise and quick aqueous liquid sampling and pipetting. The microfluidic-based dispenser features...
Optical detection technique is critical for biomedical applications. The technique for optical fiber coupling is crucial for many optical detection applications. This study reports a new active two-axis micro coupler for buried optical fibers, which are commonly used for on-chip optical detection in microfluidic systems. The active micro coupler comprising air chambers, optical fiber channels, and...
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