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This study proposes a circuit architecture suitable for designing a wide dynamic range current-to-time converter, and suitable for potentiostat design meeting different requirements. Therefore, this study provides an efficient way to make trade-offs among the parameters, such as dynamic range, sampling frequency, resolution, power dissipation, and chip area. A time-based potentiostat for wide dynamic...
In this paper, we design a signal processing circuit for quartz crystal microbalance (QCM) biosensors. The proposed signal processing circuit, which consists of two oscillators, a mixer, a low-pass filter, can be used to measure small amount of QCM biosensors' frequency variation at a fundamental resonance frequency. Based on the principle of heterodyne technique, the QCM biosensors' frequency variation...
The U.S. FDA allows a maximum of 72 mg of caffeine per 12 oz. serving (6 mg/oz) and the tolerance to sleep disruption effects of caffeine develops after consuming 400 mg/day of caffeine 3 times for a week. However, it is still hard for people to estimate how much caffeine is intake daily. On the other hand, (-)epigallocatechin gallate (EGCG) is studied a potent antioxidant that may have therapeutic...
In this paper, it demonstrates a CMOS-compatible transducer for creatinine detection. Different with traditional application of ISFET (Ion Selective Field Effect Transistor), it is not for the hydrogen ion detection. To combine the CMOS MEMS platform with MIP (Molecular Imprinting Polymer) micro coating technologies, the developed MlP-gate ISFET could be used for the detecting of creatinine. The experiment...
In this paper, we propose a low-cost and portable cyclic voltammetry potentiostat for the electrochemical dopamine biosensor designed with incorporation with artificial antibody (e.g. dopamine-imprinted polymers) as the sensing element. Its performance is evaluated by comparing the calibration curves of a dopamine biosensor with those obtained from very expensive commercial equipment. Experimental...
In this paper, we propose an inductively powered converter to convert the incoming RF energy into a DC voltage (3.3 V) which powers up the biochemical sensor signal processing system. The converter, which is constructed by clamper, voltage limiter, rectifier, and LDO regulator, is capable of delivering more than 330 muW from a receiver coil to the implant circuitry. The chip area is 0.12times0.48...
For implantable biosensor applications which require a low-cost signal processing unit that features ultra-low power and low-voltage capability as well, this paper proposes a solution by merging switched-opamp technique and foreground digital calibration into a single 10-bit ADC. Utilization of the switched-opamp technique allows for low supply operation down to 0.7 V. The insufficient gain associated...
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