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Cyst nematodes induce a multicellular feeding site within roots called a syncytium. It remains unknown how root cells are primed for incorporation into the developing syncytium. Furthermore, it is unclear how CLAVATA3/EMBRYO SURROUNDING REGION (CLE) peptide effectors secreted into the cytoplasm of the initial feeding cell could have an effect on plant cells so distant from where the nematode is...
The organization of the cellular interior gives rise to properties including metabolic channeling and micro‐compartmentalization of signaling. Here, we use a lattice model of molecular crowding, together with literature‐derived protein interactions and abundances, to describe the molecular organization and stoichiometry of local cellular regions, showing that physical protein–protein interactions...
Identifying repetitive gene sequences occurring within DNA sequences that span a collection of species is a challenge that is conceptually simple yet computationally challenging. Biological research suggests that certain regions within genomic sequences may be unchanged for hundreds of millions of years; understanding and identifying these highly preserved regions is a major challenge faced by bioinformaticians...
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