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To explore the effect of Survivin siRNA on U251 and C6 cells proliferation and apoptosis in vitro and rat glioma in vivo. Both cells lines were transfected with plasmids. Survivin, Bcl-2, c-Myc, cyclin D1, and caspase3 expression in U251 cells were analyzed by Western blot. The cell proliferation and apoptosis were determined by MTT, flow cytometry, and AO/EB assays. C6 glioma model was constructed...