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Increased myocardial stiffness in aging and diabetes that may result in pathologies such as diastolic dysfunction has been attributed, in part, to an increase in cross linking of extracellular matrix proteins such as collagen. With the development of new approaches to cardiovascular therapy, it becomes increasingly important to develop noninvasive approaches for monitoring changes in myocardial cross...
Measurements from many laboratories indicate that on average the phase velocity of ultrasonic waves propagating in bone decreases with increasing frequency. This negative dispersion in bone is inconsistent with the nearly local approximation to the Kramers-Kronig relations with one subtraction that relates attenuation to dispersion. We hypothesized that observed negative dispersion in bone might result...
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