Search results for: Andreas Posa

Items from 1 to 8 out of 8 results

article

P/Q‐type calcium channel antibody‐associated headache disorder (P/Q‐HaND)

Andreas Posa, Malte Kornhuber

Pain Practice > 24 > 6 > 871 - 872

article

Jitter patterns in conventional concentric needle electromyography recordings of regenerating motor units

Andreas Posa, Andrej Temneanu, Alexander Emmer, Thomas Langer, more

Muscle & Nerve > 62 > 5 > 593 - 596

Background The time interval between two potential components of the same motor unit potential (MUP) is measured for jitter analysis. Enhanced jitter is generally thought to result from impaired neuromuscular transmission as occurs in myasthenia gravis or during reinnervation. Methods Within a database of conventional video‐electromyography (EMG) recordings 4 MUP with peculiar jitter patterns were...

article

Spontaneous continuous motor unit single discharges

Andreas Posa, Izabela Niśkiewicz, Valerian Raescu, Alexander Emmer, more

Muscle & Nerve > 61 > 3 > 387 - 390

Introduction Motor unit hyperexcitability (MUH) may become manifest in needle electromyography (EMG) recordings as fasciculation potentials, myokymic discharges, or neuromyotonic discharges. Here, we describe a further MUH phenomenon. Methods Needle EMG recordings of the Neurology Hospital of Halle (Saale) stored in a video mode as .wav data between 2000 and 2015 were screened for spontaneous continuous...

article

Myositis in Lewis rats induced by the superantigen Staphylococcal enterotoxin A

Alexander Emmer, Abimbola Abobarin-Adeagbo, Andreas Posa, Berit Jordan, more

Molecular Biology Reports > 2019 > 46 > 4 > 4085-4094

The aetiology of inflammatory myopathies is not clearly known. A predominance of activated Cd8+ T lymphocytes in inflammatory infiltrates has already been detected. Superantigens activate lymphocytes in an oligoclonal manner. In the present investigation, we investigated local effects after injection of the superantigen (Sag) Staphylococcus enterotoxin A (SEA) in the quadriceps femoris muscle of Lewis...

article

Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial

Albert C Ludolph, Joachim Schuster, Johannes Dorst, Luc Dupuis, more

The Lancet Neurology > 2018 > 17 > 8 > 681-688

Rasagiline, a monoamine oxidase B inhibitor with neuroprotective potential in Parkinson's disease, has shown a disease-modifying effect in the SOD1-Gly93Ala low-expressing mouse model of amyotrophic lateral sclerosis, both alone and in combination with riluzole. We sought to test whether or not rasagiline 1 mg/day can prolong survival in patients with amyotrophic lateral sclerosis also receiving riluzole...

article

Dysautonomic polyneuropathy as a variant of chronic inflammatory “demyelinating” polyneuropathy?

Hans-Heinrich Wolf, Malte Erich Kornhuber, Joachim Weis, Andreas Posa

Clinical Autonomic Research > 2016 > 26 > 4 > 303-305

This report describes the clinical course over almost one decade of a male patient presenting with immune-mediated pure autonomic neuropathy resembling a distinct variant of chronic dysimmune polyneuropathies. We suppose autoantibodies directed against epitopes on autonomic axons or neurons causative for the symptoms.

article

Schirmer strip vs. capillary tube method: Non-invasive methods of obtaining proteins from tear fluid

Andreas Posa, Lars Bräuer, Martin Schicht, Fabian Garreis, more

Annals of Anatomy > 2013 > 195 > 2 > 137-142

Human tear fluid is a complex mixture containing over 500 solute proteins, lipids, electrolytes, mucins, metabolites, hormones and desquamated epithelial cells as well as foreign substances from the ambient air. Little is known to date about the function of most tear components. The efficient and gentle collection of tear fluid facilitates closer investigation of these matters. The objective of the...

article

Functional relationship between cationic amino acid transporters and β-defensins: Implications for dry skin diseases and the dry eye

Kristin Jäger, Fabian Garreis, Andreas Posa, Matthias Dunse, more

Annals of Anatomy > 2010 > 192 > 2 > 65-69

The ocular surface, constantly exposed to environmental pathogens, is particularly vulnerable to infection. Hence an advanced immune defence system is essential to protect the eye from microbial attack. Antimicrobial peptides, such as β-defensins, are essential components of the innate immune system and are the first line of defence against invaders of the eye. High concentrations of l-arginine and...

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Keywords

JITTER (2)
ANIMAL MODEL (1)
AUTONOMIC DISORDER (1)
AXONAL SPROUTING (1)
CAPILLARY TUBE METHOD (1)
CATIONIC AMINO ACID TRANSPORTER (1)
CD8+ T-LYMPHOCYTES (1)
CHRONIC DYSIMMUNE POLYNEUROPATHY (1)
CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY (CIDP) (1)
CLINICAL ELECTROPHYSIOLOGY (1)
CONCENTRIC NEEDLE ELECTROMYOGRAPHY (1)
DRY EYE (1)
HEART RATE VARIABILITY (HRV) (1)
INFLAMMATORY DISEASES (1)
L-ARGININE (1)
L-LYSINE (1)
MICROARRAY ANALYSIS (1)
MOTOR UNIT HYPEREXCITABILITY (1)
MOTOR UNIT POTENTIAL (1)
MYOSITIS (1)
NEEDLE ELECTROMYOGRAPHY (1)
NEUROMUSCULAR JUNCTION (1)
NEUROMYOTONIA (1)
OCULAR SURFACE (1)
PROTEOMICS (1)
REINNERVATION (1)
SCHIRMER STRIP (1)
SPONTANEOUS ACTIVITY (1)
STAPHYLOCOCCAL ENTEROTOXIN A (SEA) (1)
SUPERANTIGEN (1)
SURFACTANT PROTEINS (1)
SYMPATHETIC SKIN RESPONSE (SSR) (1)
TEAR FLUID (1)
Β-DEFENSINS (1)
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Search results for: Andreas Posa

P/Q‐type calcium channel antibody‐associated headache disorder (P/Q‐HaND)

Jitter patterns in conventional concentric needle electromyography recordings of regenerating motor units

Spontaneous continuous motor unit single discharges

Myositis in Lewis rats induced by the superantigen Staphylococcal enterotoxin A

Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial

Dysautonomic polyneuropathy as a variant of chronic inflammatory “demyelinating” polyneuropathy?

Schirmer strip vs. capillary tube method: Non-invasive methods of obtaining proteins from tear fluid

Functional relationship between cationic amino acid transporters and β-defensins: Implications for dry skin diseases and the dry eye

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