Lucy Platt

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Commentary on Hancock et al. (2020): Low dead space syringes are just one component of an integrated package of care needed to tackle HCV and social exclusion among people who inject drugs

Lucy Platt, Magdalena Harris, Sedona Sweeney

Addiction > 115 > 4 > 714 - 715

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Prevalence and burden of HBV co‐infection among people living with HIV: A global systematic review and meta‐analysis

Lucy Platt, Clare E. French, Catherine R. McGowan, Keith Sabin, more

Journal of Viral Hepatitis > 27 > 3 > 294 - 315

Globally, in 2017 35 million people were living with HIV (PLHIV) and 257 million had chronic HBV infection (HBsAg positive). The extent of HIV‐HBsAg co‐infection is unknown. We undertook a systematic review to estimate the global burden of HBsAg co‐infection in PLHIV. We searched MEDLINE, Embase and other databases for published studies (2002‐2018) measuring prevalence of HBsAg among PLHIV. The review...

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Assessing risk of HIV and hepatitis C among people who inject drugs in East Africa: Findings from a rapid assessment

Lucy Platt, Camille May Stengel, Menus Nkurunziza, Denis Muhangi, more

Journal of Viral Hepatitis > 26 > 7 > 926 - 929

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What determines violence among female sex workers in an intimate partner relationship? Findings from North Karnataka, south India

Prakash Javalkar, Lucy Platt, Ravi Prakash, Tara Beattie, more

BMC Public Health > 2019 > 19 > 1 > 1-14

Background Like other women in India, female sex workers (FSWs) frequently experience violence from their intimate partners (IPs)-a reality that increases their risk of acquiring HIV or other sexually transmitted infections. Less is known about the nature of these intimate relationships or what aspect of the relationship increases the risk of IP violence (IPV). We measured the prevalence and determinants...

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Evaluating the cost‐effectiveness of existing needle and syringe programmes in preventing hepatitis C transmission in people who inject drugs

Sedona Sweeney, Zoe Ward, Lucy Platt, Lorna Guinness, more

Addiction > 114 > 3 > 560 - 570

Aim To evaluate the cost‐effectiveness of needle and syringe programmes (NSPs) compared with no NSPs on hepatitis C virus (HCV) transmission in the United Kingdom. Design Cost‐effectiveness analysis from a National Health Service (NHS)/health‐provider perspective, utilizing a dynamic transmission model of HCV infection and disease progression, calibrated using city‐specific surveillance and survey...

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Impact of current and scaled‐up levels of hepatitis C prevention and treatment interventions for people who inject drugs in three UK settings—what is required to achieve the WHO's HCV elimination targets?

Zoe Ward, Lucy Platt, Sedona Sweeney, Vivian D. Hope, more

Addiction > 113 > 9 > 1727 - 1738

Aims To estimate the impact of existing high‐coverage needle and syringe provision (HCNSP, defined as obtaining more than one sterile needle and syringe per injection reported) and opioid substitution therapy (OST) on hepatitis C virus (HCV) transmission among people who inject drugs (PWID) in three UK settings and to determine required scale‐up of interventions, including HCV treatment, needed to...

article

Fentanyl self-testing outside supervised injection settings to prevent opioid overdose: Do we know enough to promote it?

Catherine R. McGowan, Magdalena Harris, Lucy Platt, Vivian Hope, more

International Journal of Drug Policy > 2018 > 58 > C > 31-36

Since 2013, North America has experienced a sharp increase in unintentional fatal overdoses: fentanyl, and its analogues, are believed to be primarily responsible. Currently, the most practical means for people who use drugs (PWUD) to avoid or mitigate risk of fentanyl-related overdose is to use drugs in the presence of someone who is in possession of, and experienced using, naloxone. Self-test strips...

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Needle and syringe programmes and opioid substitution therapy for preventing HCV transmission among people who inject drugs: findings from a Cochrane Review and meta‐analysis

Lucy Platt, Silvia Minozzi, Jennifer Reed, Peter Vickerman, more

Addiction > 113 > 3 > 545 - 563

Aims To estimate the effects of needle and syringe programmes (NSP) and opioid substitution therapy (OST), alone or in combination, for preventing acquisition of hepatitis C virus (HCV) in people who inject drugs (PWID). Methods Systematic review and meta‐analysis. Bibliographic databases were searched for studies measuring concurrent exposure to current OST (within the last 6 months) and/or NSP...

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Prevalence and burden of HCV co-infection in people living with HIV: a global systematic review and meta-analysis

Lucy Platt, Philippa Easterbrook, Erin Gower, Bethan McDonald, more

The Lancet Infectious Diseases > 2016 > 16 > 7 > 797-808

At global level, there are 37 million people infected with HIV and 115 million people with antibodies to hepatitis C virus (HCV). Little is known about the extent of HIV–HCV co-infection. We sought to characterise the epidemiology and burden of HCV co-infection in people living with HIV. In this systematic review and meta-analysis we searched MEDLINE, Embase, CINAHL+, POPLINE, Africa-wide Information,...

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Sex work amongst people who inject drugs in England, Wales and Northern Ireland: Findings from a National Survey of Health Harms and Behaviours

Sara Croxford, Lucy Platt, Vivian D. Hope, Katelyn J. Cullen, more

International Journal of Drug Policy > 2015 > 26 > 4 > 429-433

•One in seven PWID in EW&NI had a lifetime experience of sex work.•Sex work was found not to be associated with blood-borne viral infections.•SWs were significantly more vulnerable due to imprisonment and homelessness.•Harm reduction service provision needs to be maintained to reduce transmission of BBVs.•Services need to cater for the gendered differences in vulnerabilities amongst PWID.

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Large-scale implementation of alcohol brief interventions in new settings in Scotland: a qualitative interview study of a national programme

Niamh Fitzgerald, Lucy Platt, Susie Heywood, Jim McCambridge

BMC Public Health > 2015 > 15 > 1 > 1-11

Background This study aimed to explore experiences of implementation of alcohol brief interventions (ABIs) in settings outside of primary healthcare in the Scottish national programme. The focus of the study was on strategies and learning to support ABI implementation in settings outside of primary healthcare in general, rather on issues specific to any single setting. Methods 14 semi-structured...

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Controlling HIV among people who inject drugs in Eastern Europe and Central Asia: Insights from modelling

Peter Vickerman, Lucy Platt, Emma Jolley, Tim Rhodes, more

International Journal of Drug Policy > 2014 > 25 > 6 > 1163-1173

Although there is evidence of the effectiveness of needle and syringe programme (NSP), opioid substitution therapy (OST) and antiretroviral therapy (ART) in reducing HIV prevalence, most Central and Eastern European sub-regions still have low or no coverage of most or all of these interventions.We conducted a modelling analysis to consider the potential impact on HIV incidence and prevalence of OST,...

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Illicit drugs in Central Asia: What we know, what we don’t know, and what we need to know

Alisher Latypov, Jean-Paul Grund, Nabila El-Bassel, Lucy Platt, more

International Journal of Drug Policy > 2014 > 25 > 6 > 1155-1162

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Health benefits, costs, and cost-effectiveness of earlier eligibility for adult antiretroviral therapy and expanded treatment coverage: a combined analysis of 12 mathematical models

Jeffrey W Eaton, Nicolas A Menzies, John Stover, Valentina Cambiano, more

The Lancet Global Health > 2014 > 2 > 1 > e23-e34

New WHO guidelines recommend initiation of antiretroviral therapy for HIV-positive adults with CD4 counts of 500 cells per μL or less, a higher threshold than was previously recommended. Country decision makers have to decide whether to further expand eligibility for antiretroviral therapy accordingly. We aimed to assess the potential health benefits, costs, and cost-effectiveness of various eligibility...

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Tuberculosis, injecting drug use and integrated HIV-TB care: A review of the literature

Pippa Grenfell, Ricardo Baptista Leite, Richard Garfein, Smiljka de Lussigny, more

Drug and Alcohol Dependence > 2013 > 129 > 3 > 180-209

People who inject drugs (PWID) are at increased risk of tuberculosis (TB) and reduced retention in treatment. There is a need to document strategies for integrated delivery of HIV, TB and drug dependency care.This article reviews the literature on rates of TB mono- and co-infection, and published and grey literature descriptions of TB and HIV-TB care, among PWID.Latent TB infection prevalence was...

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HIV infection and risk behaviour of primary fentanyl and amphetamine injectors in Tallinn, Estonia: Implications for intervention

Ave Talu, Kristiina Rajaleid, Katri Abel-Ollo, Kristi Rüütel, more

International Journal of Drug Policy > 2010 > 21 > 1 > 56-63

Following a heroin shortage, fentanyl and 3-methylfentanyl, known as “China White” and “White Persian”, have become the most widely used drugs, along with amphetamine, among injecting drug users (IDUs) in Tallinn, Estonia.In order to assess the relationships between the injection of fentanyl and amphetamine, and levels of HIV prevalence and risk behaviour, 350 current IDUs were recruited using respondent-driven...

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Access to syringes in three Russian cities: Implications for syringe distribution and coverage

Anya Sarang, Tim Rhodes, Lucy Platt

International Journal of Drug Policy > 2008 > 19 > Supplement 1 > 25-36

We report findings from a multi-method study investigating drug injectors’ access to needles and syringes in three large Russian cities (Moscow, Volgograd, Barnaul).We undertook 209 qualitative interviews among drug injectors, and supplemented these with baseline data from a community-recruited survey of 1473 drug injectors.Almost all (93%; 1277) injectors used pharmacies as their main source of clean...

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Street Policing, Injecting Drug Use and Harm Reduction in a Russian City: A Qualitative Study of Police Perspectives

Tim Rhodes, Lucy Platt, Anya Sarang, Alexander Vlasov, more

Journal of Urban Health > 2006 > 83 > 5 > 911-925

We undertook a qualitative exploration of police perspectives on injecting drug use and needle and syringe access among injecting drug users (IDUs) in a Russian city which has witnessed explosive spread of HIV associated with drug injecting. Twenty-seven in-depth qualitative interviews were conducted in May 2002 with police officers of varying rank who reported having regular contact with IDUs. All...

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Exploring Barriers to ‘Respondent Driven Sampling’ in Sex Worker and Drug-Injecting Sex Worker Populations in Eastern Europe

Milena Simic, Lisa Johnston, Lucy Platt, Sladjana Baros, more

Journal of Urban Health > 2006 > 83 > 7 > 6-15

Respondent driven sampling (RDS) has been used in several counties to sample injecting drug users, sex workers (SWs) and men who have sex with men and as a means of collecting behavioural and biological health data. We report on the use of RDS in three separate studies conducted among SWs between 2004 and 2005 in the Russian Federation, Serbia, and Montenegro. Findings suggest that there are limitations...

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Methods to Recruit Hard-to-Reach Groups: Comparing Two Chain Referral Sampling Methods of Recruiting Injecting Drug Users Across Nine Studies in Russia and Estonia

Lucy Platt, Martin Wall, Tim Rhodes, Ali Judd, more

Journal of Urban Health > 2006 > 83 > 1 > 39-53

Evidence suggests rapid diffusion of injecting drug use and associated outbreaks of HIV among injecting drug users (IDUs) in the Russian Federation and Eastern Europe. There remains a need for research among non-treatment and community-recruited samples of IDUs to better estimate the dynamics of HIV transmission and to improve treatment and health services access. We compare two sampling methodologies...

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Search results for: Lucy Platt

Commentary on Hancock et al. (2020): Low dead space syringes are just one component of an integrated package of care needed to tackle HCV and social exclusion among people who inject drugs

Prevalence and burden of HBV co‐infection among people living with HIV: A global systematic review and meta‐analysis

Assessing risk of HIV and hepatitis C among people who inject drugs in East Africa: Findings from a rapid assessment

What determines violence among female sex workers in an intimate partner relationship? Findings from North Karnataka, south India

Evaluating the cost‐effectiveness of existing needle and syringe programmes in preventing hepatitis C transmission in people who inject drugs

Impact of current and scaled‐up levels of hepatitis C prevention and treatment interventions for people who inject drugs in three UK settings—what is required to achieve the WHO's HCV elimination targets?

Fentanyl self-testing outside supervised injection settings to prevent opioid overdose: Do we know enough to promote it?

Needle and syringe programmes and opioid substitution therapy for preventing HCV transmission among people who inject drugs: findings from a Cochrane Review and meta‐analysis

Prevalence and burden of HCV co-infection in people living with HIV: a global systematic review and meta-analysis

Sex work amongst people who inject drugs in England, Wales and Northern Ireland: Findings from a National Survey of Health Harms and Behaviours

Large-scale implementation of alcohol brief interventions in new settings in Scotland: a qualitative interview study of a national programme

Controlling HIV among people who inject drugs in Eastern Europe and Central Asia: Insights from modelling

Illicit drugs in Central Asia: What we know, what we don’t know, and what we need to know

Health benefits, costs, and cost-effectiveness of earlier eligibility for adult antiretroviral therapy and expanded treatment coverage: a combined analysis of 12 mathematical models

Tuberculosis, injecting drug use and integrated HIV-TB care: A review of the literature

HIV infection and risk behaviour of primary fentanyl and amphetamine injectors in Tallinn, Estonia: Implications for intervention

Access to syringes in three Russian cities: Implications for syringe distribution and coverage

Street Policing, Injecting Drug Use and Harm Reduction in a Russian City: A Qualitative Study of Police Perspectives

Exploring Barriers to ‘Respondent Driven Sampling’ in Sex Worker and Drug-Injecting Sex Worker Populations in Eastern Europe

Methods to Recruit Hard-to-Reach Groups: Comparing Two Chain Referral Sampling Methods of Recruiting Injecting Drug Users Across Nine Studies in Russia and Estonia

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