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Vascular endothelial growth factor (VEGF) stimulation and bone marrow mesenchymal stem cell (BMSC) transplantation have been implicated in the treatment of acute cerebral infarction for their pivotal roles in behavioral recovery, neuroprotection, neurogenesis, and angiogenesis. However, the effects of BMSC transplants are likely limited because of low transplant survival after acute cerebral infarction,...
Thioredoxin-1 (Trx1) has long been recognized as a redox regulator, and is implicated in the inhibition of cell apoptosis. Trx1 is essential for the maintenance of the S-nitrosylation of molecules in cells. The S-nitrosylation of Trx1 is essential for the physiological function such as preservation of the redox regulatory activity. The mechanisms underlying Trx1 denitrosylation induced by kainate...
The aim of the study is to evaluate the cell affinity of poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) (PHBV) thin films using a parallel plate flow chamber system. The PHBV thin films were modified by anhydrous ammonia gaseous plasma treatment. Mouse 3T3 fibroblast cells were seeded on bare and plasma modified PHBV thin films, respectively. A laminar flow enforces the cells on these films...
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