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The mannan binding lectin (MBL) plays a major role in innate immunity through its ability to activate complement upon binding to carbohydrate arrays on the surface of various microorganisms. The question of a possible association of the MBL structural gene polymorphism and the oligomeric state of MBL was poorly documented. For these reasons, it appears difficult to evaluate MBL in blood patients on...
Facb, fragment antigen and complement binding (this last property is shown when the fragment is involved in an immune complex); Fc, C-terminal half of the heavy-chain dimer; pFc', major C-terminal fragment released from IgG by pepsin or plasmin digestion; DFP, diisopropylphosphofluoridate; ATEE, N-acetyl-L-tyrosine ethyl ester; BAEE, N-benzoyl-L-arginine ethyl ester; TAME, p-toluene sulfonyl-L-arginine...
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