Search results for: A. Vasilaki

Items from 1 to 20 out of 21 results

article

Age-related neuromuscular deficits in reactive oxygen species generation in exercising skeletal muscle

M.J. Jackson, A. Vasilaki, N. Pollock, C. Staunton, more

Free Radical Biology and Medicine > 2016 > 96 > S1 > S13

article

Signal Transducer and Activator of Transcription (STAT) signaling b profile at the single cell level: Novel insights in the association of FOXP3+ T regulatory cells with recurrent spontaneous abortions before and after lymphocyte immunotherapy (LIT)

M. Daniilidis, E. Lamprianidou, A. Gerofotisy, G. Pantos, more

Journal of Reproductive Immunology > 2016 > 115 > C > 45

article

Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model

S.M. Robinson, J. Mann, A. Vasilaki, J. Mathers, more

Journal of Hepatology > 2013 > 59 > 2 > 318-326

Sinusoidal obstruction syndrome (SOS) following oxaliplatin based chemotherapy can have a significant impact on post-operative outcome following resection of colorectal liver metastases. To date no relevant experimental models of oxaliplatin induced SOS have been described. The aim of this project was to establish a rodent model which could be utilised to investigate mechanisms underlying SOS to aid...

article

A transgenic approach to understanding age-related loss of muscle mass and function

A. McArdle⁎, A. Kayani, A. Vasilaki, G. Sakellariou, more

Free Radical Biology and Medicine > 2012 > 53 > Supplement 1 > S261

article

Investigating the intracellular changes in ROS production and adaptive responses in muscle specific SOD1 knockout mice

G.K. Sakellariou⁎, A. Kayani, A. Vasilaki, A. Scott, more

Free Radical Biology and Medicine > 2012 > 53 > Supplement 1 > S53-S54

article

Differential effect of ischemia, hypoxia, hyperglycaemia and hypoglycaemia on the rat retinal neurotransmittion

A VASILAKI, V GRIVAS, V SOURLAS, E PAPAGEORGIOU

Acta Ophthalmologica > 88 > s246 > 0 - 0

Purpose The time‐dependent effects of glucose and oxygen alterations on retinal neurotransmission, are not fully understood. The purpose of this study was to investigate ex vivo the influence of ischemia, hypoxia, hyper‐ and hypo‐glycaemia on the excitatory and inhibitory rat retinal neurotransmission during the first 70min after an initial insult. Methods For this purpose, 3H‐D‐Aspartate and 3H‐GABA...

article

Effect of the fish oil, oxidation status and of heat treatment temperature on the volatile compounds of the produced fish feeds

K. Grigorakis, I. Giogios, A. Vasilaki, I. Nengas

Animal Feed Science and Technology > 2010 > 158 > 1-2 > 73-84

This study aimed at giving information on the fish feeds’ volatile compounds and factors affecting them, since no respective data are currently available in the literature. Two different fish oils, a standard fish oil (FO) and a sardine oil (SO) were subjected to forced oxidation (50°C and stirring for 120h) and their non-oxidized and oxidized forms were incorporated in four produced fish feeds, respectively...

article

O08 Reactive oxygen species and loss of muscle fibres during ageing

M.J. Jackson, T. Pearson, A. Vasilaki, G. Sakellariou, more

Neuromuscular Disorders > 2010 > 20 > Supplement 1 > S3

article

LB025 LONGITUDINAL ASSESSMENT OF PLASMA VITAMIN D STATUS IN PATIENTS WITH CRITICAL ILLNESS

D. Talwar, A.M. Wallace, A. Vasilaki, J. Kinsella, more

Clinical Nutrition Supplements > 2010 > 5 > 2 > 204

article

Cytokine genes polymorphisms and recurrent pregnancy loss in a Hellenic population

A. Vasilaki, M. Daniilidis, A. Gerofotis, M. Tsilipakou, more

Journal of Reproductive Immunology > 2009 > 81 > 2 > 167-168

article

Recovery of fatty acid profiles by a fish oil finishing diet under fluctuating water temperatures

E. Fountoulaki, A. Vasilaki, R. Hurtado, K. Grigorakis, more

Aquaculture > 2009 > 289 > 3-4 > 317-326

The effects of long term feeding (6 months) of commercial diets with low fish meal content and high levels of vegetable oils (69% fish oil substitution level) were determined in gilthead sea bream (110 g). A control diet containing South American fish oil (FO) was evaluated against feeds with either soybean oil (SO), palm oil (PO) or rapeseed oil (RO). Afterwards, all fish were fed a fish oil finishing...

article

Fentanyl treatment reduces GABAergic inhibition in the CA1 area of the hippocampus 24h after acute exposure to the drug

E. Kouvaras, E.K. Asprodini, I. Asouchidou, A. Vasilaki, more

Neuropharmacology > 2008 > 55 > 7 > 1172-1182

The effect of in vivo fentanyl treatment on synaptic transmission was studied in the CA1 area of the rat hippocampus. Animals were treated either with saline or fentanyl (4×80μg/kg, s.c./15min). Intracellular in vitro recordings were obtained, 24h after treatment, from CA1 pyramidal neurons. No difference in pyramidal neuron basic membrane properties or postsynaptic membrane excitability was observed...

article

Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells

A. Vasilaki, M. Csete, D. Pye, S. Lee, more

Free Radical Biology and Medicine > 2006 > 41 > 11 > 1719-1725

Increased amounts of reactive oxygen species (ROS) are generated by skeletal muscle during contractile activity, but their intracellular source is unclear. The oxidation of 2′,7′-dichlorodihydrofluorescein (DCFH) was examined as an intracellular probe for reactive oxygen species in skeletal muscle myotubes derived from muscles of wild-type mice and mice that were heterozygous knockout for manganese...

article

Adaptive responses of mouse skeletal muscle to contractile activity: The effect of age

A. Vasilaki, F. McArdle, L.M. Iwanejko, A. McArdle

Mechanisms of Ageing and Development > 2006 > 127 > 11 > 830-839

This study has characterised the time course of two major transcriptional adaptive responses to exercise (changes in antioxidant defence enzyme activity and heat shock protein (HSP) content) in muscles of adult and old male mice following isometric contractions and has examined the mechanisms involved in the age-related reduction in transcription factor activation. Muscles of B6XSJL mice were subjected...

article

Somatostatin receptors in wildtype and somatostatin deficient mice and their involvement in nitric oxide physiology in the retina

N. Mastrodimou, A. Vasilaki, A. Papadioti, M.J. Low, more

Neuropeptides > 2006 > 40 > 5 > 365-373

The present study investigated the localization and density of somatostatin (SRIF) receptor subtypes (sst _1-5 ) and SRIF–nitric oxide (NO) interactions in the retina of wildtype [WT, (+/+)] and somatostatin deficient mice [SRIF (−/−)]. Immunohistochemistry and radioligand binding studies with subsequent autoradiography were performed. Monoclonal antibodies [SRIF, protein kinase C (rod bipolar...

article

Reactive oxygen species as signals for adaptation in healthy and diseased skeletal muscle

M.J. Jackson, F. McArdle, G. Close, A. Vasilaki, more

Acta Biochimica Polonica > 2006 > 53 > Supplement 1

article

The immune response in hemodialysis patients following physical training

M. Daniilidis, E. Kouidi, F. Giagoudaki, A. Fleva, more

Sport Sciences for Health > 2004 > 1 > 1 > 11-16

The effects of mild physical training on the cell-mediated and humoral immune responses were studied in 18 patients with end-stage renal disease (6.5±5.2 years on hemodialysis) participating in a six month exercise renal rehabilitation program. They were matched with 14 untrained patients for sex, age, years on hemodialysis and causes of renal disease. Serum immunoglobulins (IgA, IgM, IgG), IgG...

article

Octreotide and opioids reduce the rate of proliferation of human hepatocellular carcinoma (HCC) cell line HEPG2, with parallel increase of nitric oxide (NO) production

G. Notas, M. Kampa, A. Vasilaki, C. Xidakis, more

Journal of Hepatology > 2003 > 38 > Supplement 2 > 103

article

Somatostatin mediates nitric oxide production by activating sst ₂ receptors in the rat retina

A. Vasilaki, M. Mouratidou, S. Schulz, K. Thermos

Neuropharmacology > 2002 > 43 > 5 > 899-909

Somatostatin and its receptors (ssts) are found in the retina. Recent evidence suggested the involvement of sst ₂ _A and sst ₂ _B receptors in the regulation of nitric oxide (NO) (). In this study, we investigated further the localization of sst ₁ , sst ₃ -sst ₅ , and the possible involvement of all subtypes, present in the rat retina, in the regulation...

article

A phase II trial of concomitant brachytherapy and chemotherapy with docetaxel and cisplatinum combined with surgery and external radiotherapy for locally advanced uterine carcinoma

H. Varveris, F. Lyraraki, S. Kachris, M. Mazonakis, more

European Journal of Cancer > 1999 > 35 > Supplement 4 > S233

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Search results for: A. Vasilaki

Age-related neuromuscular deficits in reactive oxygen species generation in exercising skeletal muscle

Signal Transducer and Activator of Transcription (STAT) signaling b profile at the single cell level: Novel insights in the association of FOXP3+ T regulatory cells with recurrent spontaneous abortions before and after lymphocyte immunotherapy (LIT)

Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model

A transgenic approach to understanding age-related loss of muscle mass and function

Investigating the intracellular changes in ROS production and adaptive responses in muscle specific SOD1 knockout mice

Differential effect of ischemia, hypoxia, hyperglycaemia and hypoglycaemia on the rat retinal neurotransmittion

Effect of the fish oil, oxidation status and of heat treatment temperature on the volatile compounds of the produced fish feeds

O08 Reactive oxygen species and loss of muscle fibres during ageing

LB025 LONGITUDINAL ASSESSMENT OF PLASMA VITAMIN D STATUS IN PATIENTS WITH CRITICAL ILLNESS

Cytokine genes polymorphisms and recurrent pregnancy loss in a Hellenic population

Recovery of fatty acid profiles by a fish oil finishing diet under fluctuating water temperatures

Fentanyl treatment reduces GABAergic inhibition in the CA1 area of the hippocampus 24h after acute exposure to the drug

Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells

Adaptive responses of mouse skeletal muscle to contractile activity: The effect of age

Somatostatin receptors in wildtype and somatostatin deficient mice and their involvement in nitric oxide physiology in the retina

Reactive oxygen species as signals for adaptation in healthy and diseased skeletal muscle

The immune response in hemodialysis patients following physical training

Octreotide and opioids reduce the rate of proliferation of human hepatocellular carcinoma (HCC) cell line HEPG2, with parallel increase of nitric oxide (NO) production

Somatostatin mediates nitric oxide production by activating sst ₂ receptors in the rat retina

A phase II trial of concomitant brachytherapy and chemotherapy with docetaxel and cisplatinum combined with surgery and external radiotherapy for locally advanced uterine carcinoma

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