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Legionella pneumophila is a freshwater bacterium that replicates in predatory amoeba and alveolar macrophage. The ability of L. pneumophila to thrive in eukaryotic host cells is conferred by the Legionella containing vacuole (LCV). Formation and intracellular trafficking of the LCV are governed by an arsenal of effector proteins, many of which are secreted by the Icm/Dot Type 4 Secretion System....
Tellina virus 1 is an aquabirnavirus that was isolated from the sand‐dwelling marine bivalve mollusc Tellina tenuis. The self‐encoded protease viral protein 4 (VP4) processes its own polyprotein to yield the individual proteins VP2 and VP3 that are required for viral assembly. VP4 protease utilizes a serine–lysine catalytic dyad in its mechanism. A full‐length VP4 construct was overexpressed in Escherichia coli...
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