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Two-step hydrolysis of husk obtained from rice (Oryza sativa) was investigated as one of the monocotyledonous angiosperms under the semi-flow hot-compressed water treatment at 230°C/10MPa/15min (1st stage) and 270°C/10MPa/30min (2nd stage). Prior to the hot-compressed water treatment, cold-water extraction at 20°C/10MPa/30min was performed. It was found that some inorganic constituents and free neutral...
Although novel agents effective against malignant mesothelioma (MM) have been developed, the prognosis of patients with MM is still poor. We generated a DNA-chimeric siRNA against polo-like kinase-1 (PLK-1), which was more stable in human serum than the non-chimeric siRNA. The chimeric PLK-1 siRNA inhibited MM cell proliferation through the induction of apoptosis. Next, we investigated the effects...
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