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The prevalence of celiac disease (CD) in patients with type 1 diabetes (T1D) has been reported to be 5–7 times higher than in the general population. Risk factors for co‐occurrence of both diseases have not been entirely established. The aim of our study was to analyze possible impact of human leukocyte antigen (HLA) class I and killer cell immunoglobulin‐like receptors (KIRs) on the co‐occurrence...
Celiac disease (CD) is more common in individuals with insulin dependent diabetes mellitus (T1D) than in the general population. HLA class II molecules DQ8 (DQB1*0302‐DQA1*0301) and DQ2 (DQB1*0201‐DQA1*0501) have been identified as key genetic risk factors in both diseases. While DQ8 conveys a higher risk for T1D, DQ2 is more frequent in CD. Less is known about the contribution of HLA class I. The...
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