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HLA‐DRB3 allelic polymorphism on HLA‐DRB1*03:01‐positive haplotypes was investigated among 104 cadaveric donors typed for HLA‐A, ‐B, ‐DRB1, and ‐DRB3. Only HLA‐DRB3*01:01:02 and ‐DRB3*02:02:01:01 alleles were detected among HLA‐DRB1*03:01‐positive individuals and their distribution depended on HLA‐B*08 presence: nearly all HLA‐B*08‐positive samples carried DRB3*01:01:02, while HLA‐DRB3*02:02:01:01...
The aim of the present study was to investigate frequency and haplotype distribution of DRB4 alleles in the Croatian population. The investigated sample consisted of 288 cadaveric donor samples positive for one of the DR53 alleles. HLA‐A, ‐B, ‐C, ‐DRB1, and ‐DQB1 typing was performed using the polymerase chain reaction‐sequence specific primers (PCR‐SSP) low resolution method, while HLA‐DRB4 and selected...
The aim of the study was to evaluate the presence of nonfrequent, rare and very rare alleles among Croats and to estimate whether they are associated with specific alleles at other human leukocyte antigen (HLA) loci. This retrospective study included the typing results from the last 10 years; total number of individuals included was approximately 45,000. Among 17 alleles so far observed only once...
The determination of human leucocyte antigen (HLA)‐A, HLA‐B and HLA‐DRB1 alleles in the routine procedure of a volunteer hematopoietic stem cell (HSC) donor's registration in the Croatian Bone Marrow Donor Registry (CBMDR) is performed to enhance the odds of finding a suitable HLA compatible donor for patients in need of a HSC transplantation worldwide. However, besides its original purpose, it also...
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