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Breast cancer is the most common type of invasive cancer in females. It accounts for 18.2% of all cancer deaths worldwide. Although somatic mutations play important roles in cancer development and prognosis, the outcome predictions are largely based on the expression of marker genes. We submit that developing an innovative prognostic model incorporating somatic mutations with gene expression can improve...
Pulmonary adenocarcinoma in situ (AIS) is an intermediate subtype of lung adenocarcinoma that exhibits non-invasive growth patterns, but can develop into invasive. Almost 100% of AIS patients can be cured with complete resection. In contrast, the five-year survival rate for those diagnosed with invasive lung adenocarcinoma is only about 4%. In order to get a better understanding of adenocarcinoma...
The emission of light from electrons passing near a grating includes resonant plasmonic features and Smith-Purcell collective excitations. We observe both and distinguish between them, finding surprising robustness to disorder in the Smith-Purcell radiation.
A novel phase-locking method, which locks cavity phase based on the pulse patterns detected from each cavity, has stabilized the output pulse intensity in a four-cavity Coherent Pulse Stacking experiment.
The various higher-harmonic orders generated in solids exhibit qualitatively different sensitivity to driver-pulse ellipticity, resulting from a different response of intraband and interband dynamics. Non-zero driver-pulse ellipticity permits harmonic cutoff extension and circularly polarized higher-harmonics.
We perform simulations to model electron energy loss spectroscopy of aluminum nanodisk surface plasmons. Nanodisk geometry and e-beam position determine excitation and energy of plasmonic modes. Multipolar modes are explained with a circulating waveguide model.
To investigate novel engine and fuel designs for greener aviation, instrumentation is required that can spatially and temporally resolve gas concentrations within aero-engine exhausts. This paper presents work towards a parallel, high-speed, distributed data acquisition (DAQ) system that employs in-situ demodulation of tunable diode laser absorption spectroscopy (TDLAS) signals. We briefly describe...
Soliton microcombs are demonstrated at both 1064 nm and 778 nm by dispersion-engineering on-chip silica resonators. These are the shortest wavelength soliton microcombs demonstrated to date and have potential applications in optical clocks and metrology.
A microresonator having Q factors greater than 200 million and featuring a silicon-nitride integrated coupling waveguide is described. The device is a critical advance for new microcavity applications requiring integrated, ultra-high-Q and millimeter-scale cavities.
Chiral metamirrors can reflect one circularly polarized light without changing its handedness, while almost completely absorb the other, which would have many potential applications in engineering. In this paper, recent progresses of our group on the chiral metamirrors are reviewed. Firstly, we discuss the general method to design the chiral metamirrors under the framework of Jones calculus. The structural...
Heterostructures of carbon nanotube on graphene, CNT-graphene, with two graphene layers connected by a CNT normal to the graphene planes, are investigated using first-principle calculations, leading to computed density of states (DOS) and electron transmission spectra. Based on these results, the structure consisting of graphene and a (4,4) CNT is determined to be metallic while that of graphene and...
Wafer reconstitution is a vital process for serving as a buffer to decouple the processing developments between IC fabrication and electronics packaging. By this approach, the IC packaging is then independent from the chip processing. However, such a process brings numerous mechanical loadings during molding and curing phases. Without carefully planning, failures such as die-shifting and excessive...
Time-frequency representation (TFR), revealing time and frequency features of signals simultaneously, has attracted increasingly attention in non-stationary signal processing. The existing TFRs can be mainly divided into two categories: non-parameterized and parameterized TFRs. The former has been widely applied on various non-stationary signals, while the latter is of particular interesting since...
A bidirectional fiber-IVLLC and fiber-wireless convergence system based on two orthogonally polarized optical sidebands for hybrid CATV/MMW/BB signal transmission is proposed and demonstrated. Two orthogonally polarized optical sidebands are transmitted over a 40-km SMF transport to effectively reduce the fiber dispersion and the distortion. The approach presented in this work signifies the advancements...
Recently, we introduced an ab-initio time-dependent density-functional theory (TDDFT) framework that allows us to investigate the coupled interplay between the interband and intraband mechanisms of high-harmonic generation (HHG) from solids [1] without making a-priori model assumptions or strong approximations. Here, using HHG experiments on bulk silicon samples combined with TDDFT simulations, we...
4,4’-N,N’-dicarbazolebiphenyl (CBP), a wide bandgap organicmaterialwith a lowglass transition temperature, was doped with WO3 or MoO3 through co-deposition and sequential deposition. The doping effects were studied via comparative characterization of hole-only devices and simple green organic light-emitting diodes. Doped films prepared by sequential deposition of alternative 0.5 nm oxide and 3–10...
In this paper, the millimeter-wave circuit miniaturization techniques using BCMLR and interdigital resonators are introduced. Using these structures, the physical size of the on-chip filter can be dramatically reduced. The designed BPFs are implemented in standard 0.13-μm SiGe and 0.1-μm GaAs technologies for concept approval. Compared with other state-of-the-art work at millimeter-wave frequencies,...
Spin Transfer Torque Magnetic Random Access Memories (STT-MRAM) are based on Magnetic Tunnel Junctions (MTJs) made out of two ferromagnetic electrodes separated by a MgO tunnel barrier.
The pSTT MRAM array with stepped structure MTJ is fully integrated with standard 0.18 µm CMOS process. Using a low power etch process greatly improves the uniformity of MR and RP. The bit pattern is randomized with a voltage method and a cost-effective field method; the latter can be incorporated into wafer processing. We showed the bit pattern is unpredictable under the same sub-critical stimulation,...
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