Search results for: Guang Xu

Items from 1 to 20 out of 400 results

article

A Coupling‐Induced Assembly Strategy for Constructing Artificial Shell on Mitochondria in Living Cells

Ben‐Li Song, Jia‐Qi Wang, Guang‐Xu Zhang, Ning‐Bo Yi, more

Angewandte Chemie > 136 > 45 > n/a - n/a

The strategy of in vivo self‐assembly has been developed for improved enrichment and long‐term retention of anticancer drug in tumor tissues. However, most self‐assemblies with non‐covalent bonding interactions are susceptible to complex physiological environments, leading to weak stability and loss of biological function. Here, we develop a coupling‐induced assembly (CIA) strategy to generate covalently...

article

A Coupling‐Induced Assembly Strategy for Constructing Artificial Shell on Mitochondria in Living Cells

Ben‐Li Song, Jia‐Qi Wang, Guang‐Xu Zhang, Ning‐Bo Yi, more

Angewandte Chemie International Edition > 63 > 45 > n/a - n/a

article

Does cytomegalovirus infection and antiviral therapy affect prognosis of biliary atresia? A real‐world retrospective cohort study

Jie Dong, Ting Xie, Bo Li, Yong Xiao, more

Journal of Medical Virology > 96 > 8 > n/a - n/a

To explore the impacts of cytomegalovirus (CMV) infection and antiviral treatment (AVT) on native liver survival (NLS) in biliary atresia (BA) infants. This retrospective cohort study included infants diagnosed as BA between January 2015 and December 2021 at Hunan Children's Hospital. CMV infection was defined by DNA polymerase chain reaction alone (DNA data set) and combination of DNA and immunoglobulin...

article

An efficient peptide ligase engineered from a bamboo asparaginyl endopeptidase

Xin‐Bo Wang, Cong‐Hui Zhang, Teng Zhang, Hao‐Zheng Li, more

The FEBS Journal > 291 > 13 > 2918 - 2936

In recent years, a few asparaginyl endopeptidases (AEPs) from certain higher plants have been identified as efficient peptide ligases with wide applications in protein labeling and cyclic peptide synthesis. Recently, we developed a NanoLuc Binary Technology (NanoBiT)‐based peptide ligase activity assay to identify more AEP‐type peptide ligases. Herein, we screened 61 bamboo species from 16 genera...

article

Monolithic Interphase Enables Fast Kinetics for High‐Performance Sodium‐Ion Batteries at Subzero Temperature

Yi‐Hu Feng, Mengting Liu, Junxiu Wu, Chao Yang, more

Angewandte Chemie International Edition > 63 > 23 > n/a - n/a

In spite of the competitive performance at room temperature, the development of sodium‐ion batteries (SIBs) is still hindered by sluggish electrochemical reaction kinetics and unstable electrode/electrolyte interphase under subzero environments. Herein, a low‐concentration electrolyte, consisting of 0.5M NaPF₆ dissolving in diethylene glycol dimethyl ether solvent, is proposed for SIBs working at...

article

Monolithic Interphase Enables Fast Kinetics for High‐Performance Sodium‐Ion Batteries at Subzero Temperature

Yi‐Hu Feng, Mengting Liu, Junxiu Wu, Chao Yang, more

Angewandte Chemie > 136 > 23 > n/a - n/a

article

Will sentiment analysis need subculture? A new data augmentation approach

Zhenhua Wang, Simin He, Guang Xu, Ming Ren

Journal of the Association for Information Science and Technology > 75 > 6 > 655 - 670

Nowadays, the omnipresence of the Internet has fostered a subculture that congregates around the contemporary milieu. The subculture artfully articulates the intricacies of human feelings by ardently pursuing the allure of novelty, a fact that cannot be disregarded in the sentiment analysis. This paper aims to enrich data through the lens of subculture, to address the insufficient training data faced...

article

The promotion‐like effect of the M1‐STN hyperdirect pathway induced by ccPAS enhanced balance performances: From the perspective of brain connectivity

Yu‐Lin Li, Jia‐Jia Wu, Xu‐Yun Hua, Mou‐Xiong Zheng, more

CNS Neuroscience & Therapeutics > 30 > 4 > n/a - n/a

Aims The present study aimed to explore the effect of cortico‐cortical paired‐associative stimulation (ccPAS) in modulating hyperdirect pathway and its influence on balance performance. Methods Forty healthy participants were randomly allocated to the active ccPAS group (n = 20) or the sham ccPAS group (n = 20). The primary motor cortex and subthalamic nucleus were stimulated sequentially with...

article

Application of clustering strategy for automatic segmentation of tissue regions in mass spectrometry imaging

Guang Xu, Shengfeng Gan, Bo Guo, Li Yang

Rapid Communications in Mass Spectrometry > 38 > 8 > n/a - n/a

Rationale Mass spectrometry imaging (MSI) has been widely used in biomedical research fields. Each pixel in MSI consists of a mass spectrum that reflects the molecule feature of the tissue spot. Because MSI contains high‐dimensional datasets, it is highly desired to develop computational methods for data mining and constructing tissue segmentation maps. Methods To visualize different tissue regions...

article

Planar antenna array synthesis for wireless power transmission based on brain storm optimization algorithm

Qing He Zhang, Yan Shan, Zhao Yang Shen, Guang Xu Liu

Microwave and Optical Technology Letters > 66 > 1 > n/a - n/a

This study investigates the synthesis of a two‐dimensional transmitting planar antenna array for a wireless power transmission system. The antenna synthesis problem is transformed into an optimization problem under multiple constraints. Accordingly, a brainstorming optimization algorithm is utilized to optimize the element position of the planar antenna arrays under the constraints of aperture size,...

article

Synthesis of Monofluorocyclohexene via Photocatalytic Defluorinative [4+2] Annulation of gem‐Difluoroalkenes with Unactivated Alkenes

Guang‐Xu Zhang, Dong‐Sheng Li, Fei Xue, An‐Feng Chen, more

Advanced Synthesis & Catalysis > 365 > 24 > 4603 - 4608

Herein, a photocatalytic system for defluorinative [4+2] annulation of gem‐difluoroalkenes with unactivated alkenes is realized. This protocol was compatible with a broad scope of unactivated alkenes, affording the diverse monofluorocyclohexene products in 30–95% yields. Furthermore, the value of this method was demonstrated by the gram‐scale synthesis, late‐stage functionalization and synthesis of...

article

Morphological alterations of contralesional hemisphere relate to functional outcomes after stroke

Juan‐Juan Lu, Xiang‐Xin Xing, Jiao Qu, Jia‐Jia Wu, more

European Journal of Neuroscience > 58 > 5 > 3347 - 3361

The present study aimed to investigate poststroke morphological alterations contralesionally and correlations with functional outcomes. Structural magnetic resonance images were obtained from 27 poststroke patients (24 males, 50.21 ± 10.97 years) and 20 healthy controls (13 males, 46.63 ± 12.18 years). Voxel‐based and surface‐based morphometry analysis were conducted to detect alterations of contralesional...

article

Effectiveness and Accuracy of MRI‐Ultrasound Fusion Targeted Biopsy Based on PI‐RADS v2.1 Category in Transition/Peripheral Zone of the Prostate

Yunyun Liu, Shuai Wang, Guang Xu, Bangguo Zhou, more

Journal of Magnetic Resonance Imaging > 58 > 3 > 709 - 717

Background MRI‐ultrasound fusion targeted biopsy (MRI‐TBx) improves the clinically significant prostate cancer (csPCa) detection with fewer cores. However, whether systematic biopsy‐guided by transrectal ultrasound (TRUS‐SBx) can be omitted when undergoing MRI‐TBx in transition zone (TZ) and peripheral zone (PZ) remains unclear. Purpose To assess the performance and effectiveness of MRI‐TBx based...

article

FAM237A, rather than peptide PEN and proCCK56‐63, binds to and activates the orphan receptor GPR83

Hao‐Zheng Li, Ya‐Fen Wang, Xiao‐Xia Shao, Ya‐Li Liu, more

The FEBS Journal > 290 > 13 > 3461 - 3479

G protein‐coupled receptor 83 (GPR83) is primarily expressed in the brain and is implicated in the regulation of energy metabolism and some anxiety‐related behaviours. Recently, the PCSK1N/proSAAS‐derived peptide PEN, the procholecystokinin‐derived peptide proCCK56‐63, and family with sequence similarity 237 member A (FAM237A) were all reported as efficient agonists of GPR83. However, these results...

article

Cerebral ¹⁸F‐fluorodeoxyglucose metabolism alteration of reward‐ and motivation‐related regions in groups of different BMI classifications

Yu‐Jie Duan, Mou‐Xiong Zheng, Jia‐Jia Wu, Jie Ma, more

Obesity > 30 > 11 > 2213 - 2221

Objective This study explored the relationship between BMI and regional cerebral glucose metabolism and explicitly detected regions with significant differences in cerebral metabolism using positron emission tomography (PET)/magnetic resonance imaging in the resting state. Methods Corresponding PET images acquired from 220 participants were sorted into four groups according to Asian BMI standards:...

article

Enhancement of antibacterial and growth‐promoting effects of Paenibacillus polymyxa by optimizing its fermentation process

Shoude Liu, Huamei Liu, Li Zhou, Zhiguo Cheng, more

Journal of Applied Microbiology > 133 > 5 > 2954 - 2965

Aims We aimed to enhance the antibacterial and growth‐promoting effects of Paenibacillus polymyxa by improving the yield of spores, lipopeptides and indole‐3‐acetic acid (IAA) in the fermentation process. Methods and Results Through medium optimization by the response surface method and feeding fermentation, the number of spores reached 2.37 × 10⁹ cfu ml⁻¹ with an increase of 38%, the content of...

article

Development of a general bioluminescent activity assay for peptide ligases

Cong‐Hui Zhang, Xiao‐Xia Shao, Xin‐Bo Wang, Li‐Li Shou, more

The FEBS Journal > 289 > 17 > 5241 - 5258

In recent years, some peptide ligases have been identified, such as bacterial sortases and certain plant asparaginyl or prolyl endopeptidases. Peptide ligases have wide applications in protein labelling and cyclic peptide synthesis. To characterize various known peptide ligases or identify new ones, we propose a general bioluminescent activity assay via the genetic fusion of a recognition motif of...

article

Polysaccharide extract from Isatidis Radix inhibits multiple inflammasomes activation and alleviate gouty arthritis

Lutong Ren, Qiang Li, Hui Li, Xiaoyan Zhan, more

Phytotherapy Research > 36 > 8 > 3295 - 3312

The polysaccharide extract from Isatidis Radix exhibits potent antiinflammatory and antiviral activities, but the mechanism of Isatidis Radix polysaccharide (IRP) remains obscure. Herein, we reported that IRP blocked the activation of nod‐like receptor pyrin domain‐containing 3 (NLRP3) inflammasome, leading to the inhibiting of caspase‐1 cleavage and IL‐1β secretion. Mechanistically, IRP did not inhibit...

article

Letter to the editor: Selection of appropriate statistical methods for prediction model

Zhixin Huang, Dong Yang, Yan Huang, Guang Xu, more

Hepatology > 75 > 5 > 1348 - 1349

article

Effect of silver diamine fluoride on hyperplastic gingivitis in an adult with intellectual disability—A case report

Guang Xu David Lim, Jingrong Yang

Special Care in Dentistry > 42 > 1 > 73 - 79

Silver diamine fluoride 38% (SDF) may possess therapeutic effects beyond desensitization, caries prevention and arresting. We report the case of a 41‐year‐old male with intellectual disability. He had generalized gingivitis on a reduced periodontium and presented with enlarged gingiva with mobile teeth, particularly on the upper anterior and upper left. The inflammation could not be fully resolved...

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INFONA - science communication portal

Search results for: Guang Xu

A Coupling‐Induced Assembly Strategy for Constructing Artificial Shell on Mitochondria in Living Cells

A Coupling‐Induced Assembly Strategy for Constructing Artificial Shell on Mitochondria in Living Cells

Does cytomegalovirus infection and antiviral therapy affect prognosis of biliary atresia? A real‐world retrospective cohort study

An efficient peptide ligase engineered from a bamboo asparaginyl endopeptidase

Monolithic Interphase Enables Fast Kinetics for High‐Performance Sodium‐Ion Batteries at Subzero Temperature

Monolithic Interphase Enables Fast Kinetics for High‐Performance Sodium‐Ion Batteries at Subzero Temperature

Will sentiment analysis need subculture? A new data augmentation approach

The promotion‐like effect of the M1‐STN hyperdirect pathway induced by ccPAS enhanced balance performances: From the perspective of brain connectivity

Application of clustering strategy for automatic segmentation of tissue regions in mass spectrometry imaging

Planar antenna array synthesis for wireless power transmission based on brain storm optimization algorithm

Synthesis of Monofluorocyclohexene via Photocatalytic Defluorinative [4+2] Annulation of gem‐Difluoroalkenes with Unactivated Alkenes

Morphological alterations of contralesional hemisphere relate to functional outcomes after stroke

Effectiveness and Accuracy of MRI‐Ultrasound Fusion Targeted Biopsy Based on PI‐RADS v2.1 Category in Transition/Peripheral Zone of the Prostate

FAM237A, rather than peptide PEN and proCCK56‐63, binds to and activates the orphan receptor GPR83

Cerebral ¹⁸F‐fluorodeoxyglucose metabolism alteration of reward‐ and motivation‐related regions in groups of different BMI classifications

Enhancement of antibacterial and growth‐promoting effects of Paenibacillus polymyxa by optimizing its fermentation process

Development of a general bioluminescent activity assay for peptide ligases

Polysaccharide extract from Isatidis Radix inhibits multiple inflammasomes activation and alleviate gouty arthritis

Letter to the editor: Selection of appropriate statistical methods for prediction model

Effect of silver diamine fluoride on hyperplastic gingivitis in an adult with intellectual disability—A case report

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