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In recent years, some peptide ligases have been identified, such as bacterial sortases and certain plant asparaginyl or prolyl endopeptidases. Peptide ligases have wide applications in protein labelling and cyclic peptide synthesis. To characterize various known peptide ligases or identify new ones, we propose a general bioluminescent activity assay via the genetic fusion of a recognition motif of...
Commercially pure zirconium was processed by the surface mechanical attrition treatment (SMAT), and the microstructure observation showed that a gradient structure was induced. Nanoindentation measurements were taken to obtain the load–displacement curves at different depths below the treated surface. Using dimensional analysis, the local yield stress, hardness, strain hardening exponent, and elastic...
Summary Renal tubulointerstitial fibrosis is the common ending of progreβsive renal disease. It is worth developing new ways to stop the progreβs of renal fibrosis. Peroxisome proliferator-activated receptor-γ (PPARγ) agonists have been studied to treat diabetic nephropathy, cisplatin-induced acute renal injury, ischemia reperfusion injury and adriamycin nephropathy. In this study, unilateral ureteral...
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