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This study was to examine whether there is evidence for vasculogenic mimicry in osteosarcoma. In vivo and in vitro studies were conducted. Studies using hematoxylin and eosin (HE) stain and CD31 immunohistochemical stain to observe the micro vascular channels in human osteosarcoma specimens were performed. Osteosarcoma cell lines (U-20S) were also tested in vitro for their ability to form tubular...
The purpose of this study is to analyze the pelvic stability after type I resection of iliac tumor. Six adult cadaveric specimens were tested. The iliac subtotal resection models were established according to Ennecking' s type I resection. Markers were affixed to the key regions of the pelves. Axial loading from proximal lumbar was applied by MTS load cell in the gradient from ON to 500 N in the double...
The purpose of this study is to analyze the pelvic strain behavior after iliac tumor type I resection. Six adult cadaveric specimens were tested. The iliac subtotal resection models were established according to Ennecking's type I resection. The surficial strains of the defect pelvis and the intact pelvis were measured using 6 strain gauges attached to the key regions of pelvis including the site...
The purpose of this study is to investigate the stability and the stress distribution of pelvic reconstruction using fibular transplantation combined with rod-screw system fixation after type I resection. A total pelvic finite-element model including the lumbar-sacral spine, proximal femur was constructed. Three- dimensional finite element models of different implants including fibula, rod and screw...
Objective: To observe whether there is evidence for vascular channel formation by osteosarcoma cellsin vitro and to illustrate mechanism of vasculogenic mimicry in osteosarcoma.Methods: Osteosarcoma cell lines (U-2OS) were tested for their ability to form tubular networks in three-dimensional culture containing type I collagen. The structures of the tubular networks were observed under a phase contrast...
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