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Stammzellen sind an der Bildung und Entwicklung vieler Gewebe und spezialisierter Zelltypen eines Organismus beteiligt. Dabei ist die Ausbildung der Zelltypen eines menschlichen Organismus nicht auf die frhe Embryonalentwicklung beschrnkt. Auch im adulten Organismus werden stndig Zellen erneuert. So knnen z. B. bei Verletzungen durch regenerative Prozesse Organe oder Gewebe wie Leber oder Haut eingeschrnkt...
Growth factor deprivation induced cell death of the hematopoietic cell line 32Dcl3 is widely used as a model system to study apoptotic signalling pathways. Here we show that the onset of cell death after IL-3 withdrawal can be strongly delayed by either cycloheximide or actinomycin D, indicating that de novo protein synthesis is required. Subtractive cDNA library hybridization was used to identify...
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