The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
In this paper we present CFD simulations to model enzymatic reactions in microfluidic flow-through chambers. The chambers are filled with magnetic nanoparticles (MNPs). For the modeling we used the open source software OpenFOAM. The simulation settings are based on previous measurement results. The fluid flow, the effects of the magnetic nanoparticles and the enzymesubstrate reaction are being examined...
This paper presents a study on the effect of the different geometries on the velocity distributions in flow-through microchambers. The chambers are filled with magnetic nanopar-ticles and continuous flow is applied in them. Our goal was to find a good and simple geometry to ensure that the flow-through times, therefore the reaction times at most of the laminar flow lines are similar in the chamber...
Many microfluidic applications use flow-through chambers in order to store [1], measure [2] or react [3] chemicals. These chambers are usually used with paused flow, but the novel solutions enable continuous flow inside the chamber, which assures much better throughput. In [4] Computational Fluid Dynamics simulations were presented for a given channel-chamber structure, where the chambers have a volume...
In this paper we present a direct computational method for calculating thermal transfer impedances between two separate locations of a given physical structure aimed at the implementation into a field-solver based on the SUNRED (SUccessive Node REDuction) algorithm. The paper describes a further reduction method in complex frequency space based on Hankel singular values. We tested the method on a...
Biotransformation of L-phenylalanine (L-1a) and five unnatural substrates (rac-1b–f) by phenylalanine ammonia-lyase (PAL) was investigated in a novel microfluidic device (Magne-Chip) that comprises microliter volume reaction cells filled with PAL-coated magnetic nanoparticles (MNPs). Experiments proved the excellent reproducibility of enzymecatalyzed biotransformation in the chip and the excellent...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.