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The enzyme responsible for depleting a key metabolite required by biofilms, was encapsulated into poly(lactic-co-glycolic acid) PLGA nanoparticles in order to develop an adjunctive anti-biofilm treatment therapy.
Diabetes mellitus affects 347 million people worldwide, and over 80 % of diabetes deaths occur in low- and middle-income countries. Type 1 diabetes (T1D) is characterized by the attacks of the body’s own immune system on the pancreatic β-cells. In this work, we present a new CTLA-4 Ig targeting at the surface of β-cell and prepare it from Escherichia coli aiming at clearing activated T cells around...
As a two-dimensional, high-resolution, minimal-invasive monitoring method, laser speckle contrast imaging (LSCI) is widely used to measure the relative speed of cerebral blood flow (CBF) under different physiological and pathological states, i.e. before and after acupuncture. During the last decade, many improved methods (spatial, temporal, and several hybrid methods) for better estimating the contrast...
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