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Red-emitting gold nanoclusters (BSA-Au25) have been synthesized in Bovine Serum albumin and found to have a characteristic fluorescence lifetime of 1.25µs. Fluorescence anisotropy measurements of BSA-Au25 reveal a dramatic increase in protein size as the pH is reduced from 7 to 3.1, consistent with the change of BSA from N form to E form. This study suggests the possibility of exploiting fluorescent...