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The majority of the population will have low back pain in their lifetime. Low back pain correlates to degenerative pain disease (DDD) which has been linked to exposure to mechanical loads. Certain occupations involving heavy lifting also correlate with DDD. Analytical models of the spine provide estimates of loading in the spine. However, data is lacking explicitly measuring mechanical forces in the...
Low back pain is one of the leading causes of missed work. Surgical intervention is an option to those who have failed conservative therapy. The current gold standard of surgical procedures is bony fusion. Long term follow up of fusion patients has identified adjacent level disease as a complication. New motion preserving technologies aim to eliminate harmful effects on adjacent levels but have not...
The purpose of this study was to characterize the effects of cyclic mechanical loading at different frequencies on the intervertebral disc and vertebral endplates. Static, 0.5 Hz or 5 Hz loading at 5 × BW was applied to the rabbit lumbar spine in vivo 2 hours/day, 5 days/week for up to 30 weeks. Following the loading period, MRI, μCT and histology analyses were performed. Results indicate an increase...
Low back pain is a prevalent medical condition in the United States population. Degeneration of the intervertebral disc is associated with low back pain. The intervertebral disc is avascular and thus must receive nutrients via diffusion, primarily from the vertebral bodies through the endplates. One proposed mechanism for development of degeneration is through the sclerosis of the endplates and diminished...
Low back pain is growing health concern affecting 31 million Americans at any given time. Many of the risk factors for low back pain are mechanical in nature. Characterizing the axial loads, muscle recruitment, and behavior compensation during everyday motion an important step in minimizng the mechanical risk factors. The purpose of this study was to use an interbody implant to analyze the intradiscal...
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