The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
A novel device that uses acoustics to separate contaminants from blood is currently being developed. One potential application of the technology is to remove lipids that are inadvertently introduced into circulation during retransfusion of shed blood in cardiopulmonary bypass surgery, thus helping to avoid post-operative impairments such as stroke. However, the acoustic energy that is supplied to...
A portable hematocrit measurement technology is desired to allow for the rapid screening of anemia in low-resource environments. In this work, we describe the development of a microfluidic disk that is combined with a novel optical hematocrit reader to enable the screening of anemia in a point-of-care format. The system features a three-chamber microfluidic disk that interfaces with a microcentrifuge...
A nerve block training phantom is being developed for use with ultrasound systems in low-resource environments. Two design options are being pursued: make-as-needed and temporally stable. The make-as-needed design is intended for production within the low-resource environment using locally available materials. The temporally stable design will be produced in the United States and transported to the...
This paper describes a microfeature scaffold that is being developed for tissue engineering. Typically, cells are grown on scaffolds that are designed to influence and direct their phenotype. By changing one or more properties of the scaffold, such as topography, it is possible to affect cellular phenotypes, including adhesion, orientation and function. In this work, the width of microscale patterns...
The goal of this study is to design a scaffold, utilizing topographical features on the nanometer scale, to determine the relationship between those features and cellular orientation during in vitro cell culture. Ultimately the goal of this study is to control the structure of engineered tissue which can be accomplished by directing cellular orientation during growth. The control of tissue structure...
Blood glucose measurements are vital for a wide range of medical uses, including point-of-care patient testing. Typical glucose meters have been designed to operate in controlled environments, such as hospitals, and are therefore often unsuitable for use in extreme weather conditions. This paper describes a design that will allow the glucose meter to be used in a cold weather environment, thus enabling...
The developing world has a number of challenges regarding healthcare, such as insufficient training and funding to properly care for patients. One problem involves neonates that are born with Respiratory Distress Syndrome (RDS), which is a lack of surfactant in the lungs. RDS is typically treated using a Continuous Positive Airway Pressure Device (CPAP) that prevents the lungs of the neonate from...
This paper describes a method for rapid prototyping of microfluidic devices in Shrinky Dinks polymers by using a cutting plotter. The new method can produce microchannels with controlled dimensions ranging from 5.8 mm to 330 μm, and fluid tests with a dye solution showed no leakage for channel lengths over 1.5 cm. The total processing time to produce devices with this method is less than 10 minutes,...
Energy metabolism rates have been hypothesized to reflect abnormalities in diseases such as heart failure and diabetes. Using magnetic resonance imaging (MRI) technology, these rates can be imaged in multiple locations in the body. Due to similarities in muscle striations between myocardial and skeletal tissues, the metabolism of these substances will be imaged in the leg in order to increase patient...
A lab-on-a-chip device is being developed to meet the need for improved diagnostics in the developing world. This device will have the ability to run immunochromatographic assays as a method for disease detection. The device will utilize one-way valves and pressure-activated channels to conduct the assay. The successful design of a chip that conducts immunochromatographic assays could lead to the...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.