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Fluorescence biophotometry measurements require wide dynamic range (DR) and high sensitivity laboratory apparatus. Indeed, it is often very challenging to accurately resolve the small fluorescence variations in presence of high background tissue autofluorescence. There is a great need for smaller detectors combining high linearity, high sensitivity, and high-energy efficiency. This paper presents...
In this paper, we present a wireless photostimulator providing high output power from small 1.5-V Zinc-Air coin battery to stimulate light sensitized neurons. To overcome the limits of such a small energy source e.g. discharging current and voltage, the proposed photostimulator is based on a DC/DC converter and a switched capacitor circuit to provide high voltage (4 V) and high current (maximum 20...
This paper presents a fully implantable brain machine interface based on a new CMOS system-on-a-chip (SOC) including a low-power multi-channel current-reuse analog front-end (AFE), a multi-band wireless transceiver and a power management unit retrieving power from a 13.56 MHz carrier through a new 5-coil inductive link. In addition to this SOC, the proposed interface includes a low-power microcontroller,...
The demonstration will presents a battery powered multichannel wireless optogenetic headstage providing neural recording and optical stimulation capabilities simultaneously. The proposed headstage, which is entirely built using commercial off-the-shelf components, includes 32 electrophysiological recording channels and up to 32 high-power optical stimulation channels. It can process 32 neuronal signals...
This paper presents a new multimodal control interface for people living with upper-body disabilities based on a wearable wireless sensor network. The proposed body-machine interface is modular and can be easily adapted to the residual functional capacities (RFCs) of different users. A custom data fusion algorithm has been developed for emulating a joystick control using head motion measured with...
Multimodal body-machine interfaces play an important role in providing severely impaired with interaction solutions that can adapt to their functional capacities [1]. This demonstration will allow the visitors to experience an intuitive and wearable control interface, designed for people with upper body disabilities, that translates head motion, shoulder elevation and surface electromyography into...
This paper presents different miniature wireless brain computer interfaces (BCI) enabling synchronized optogenetics and electrophysiology recording for various experimental conditions. These devices, which are entirely built using commercial off-the-shelf components, are validated in-vivo with small transgenic mice. First, a system including 32 electrophysiological recording channels and up to 32...
This paper presents a wirelessly powered, fully-integrated, low-power full-duplex transceiver to support high-density and bidirectional neural implants. The transmitter (TX) uses impulse radio ultra-wide band based on an edge combining approach, and the receiver (RX) uses a 2.4-GHz on-off keying narrow band topology. The proposed transceiver provides dual band 500-Mbps TX uplink data rate and 100...
A new low-power custom integrated lock-in amplifier (LIA) with semi-digital automatic phase tuning is presented. The proposed LIA leverages a new semi-digital phase tuning peripheral loop to automatically align the relative phase of a low-amplitude input signal of known carrier with that of a reference signal to increase sensitivity while decreasing the power consumption of the LIA compared with previous...
Saliency models provide heatmaps highlighting the probability of each pixel to attract human gaze. To define image's important regions, features maps are extracted. The rarity, surprise or contrast are computed leading to conspicuity maps, showing important regions of each feature map. The final saliency map is obtained by merging these maps. The fusion process is usually a linear combination of the...
In this paper, a short-impulse ultra-wide band (UWB) transmitter is introduced to enable large-scale neural recordings within miniature brain implants including thousands of channels. The proposed impulse radio UWB transmitter uses a BPSK modulation scheme, the carrier signal of which uses only two delayed impulses to encode the transmitted signal. The proposed UWB transmitter has been implemented...
Advancement in wireless and microsystems technology have ushered in new devices that can directly interface with the central nervous system for stimulating and/or monitoring neural circuitry. In this paper, we present an ultra low-power sigma-delta analog-to-digital converter (ADC) intended for utilization into large-scale multi-channel neural recording implants. This proposed design, which provides...
Advancement in wireless and microsystems technology have ushered in new devices that can directly interface with the central nervous system for stimulating and/or monitoring neural circuitry. In this paper, we present the design of low-power CMOS integrated transceivers intended for utilization into large-scale multi-channel neural stimulating/monitoring implants. We discuss the design and the implementation...
In this Paper, we propose a new method for safe electrical neural stimulation. Current mode digital-to-analog converters are used to generate the cathodic and the anodic stimulation phases. A sample-and-hold and a window comparator circuit are used to compare the voltage of the electrode and the tissue with a target value within a safe voltage range of −50 mV to +50 mV. When the electrode voltage...
This paper presents the in vivo performances of a resource-optimized digital action potential (AP) detector featuring an adaptive threshold based on a new Sigma-delta control loop. The proposed AP detector is optimized for utilizing low hardware resources, which makes it suitable for real-time implementation on most common low-power microcontroller units (MCU). The adaptive threshold is calculated...
This paper presents a multichannel wireless op-togenetic headstage providing neural recording and optical stimulation capabilities simultaneously. The proposed headstage, which is entirely built using commercial off-the-shelf components, includes 32 electrophysiological recording channels and up to 32 high-power optical stimulation channels. It can process 32 neuronal signals in real-time with high...
Assistive Technologies (ATs) also called extrinsic enablers are useful tools for people living with various disabilities. The key points when designing such useful devices not only concern their intended goal, but also the most suitable human-machine interface (HMI) that should be provided to users. This paper describes the design of a highly intuitive wireless controller for people living with upper...
This paper presents a resources-optimized digital action potential (AP) detector featuring an adaptive threshold based on a new Sigma-delta control loop. The proposed AP detector is optimized for utilizing low hardware resources, which makes it suitable for implementation on most popular low-power microcontrollers units (MCU). The adaptive threshold is calculated using a digital control loop based...
In this paper, we present a digital spike detector using an adaptive threshold which is suitable for real time processing of 32 electrophysiological channels in parallel. Such a new scheme is based on a Sigma-delta control loop that precisely estimates the standard deviation of the amplitude of the noise of the input signal to optimize the detection rate. Additionally, it is not dependent on the amplitude...
In this paper, we propose a level shifter circuit that is able to convert signal levels of subthreshold values to super-threshold signal levels. Such a circuit is using a new voltage level shifter topology employing a level-shifting capacitor. This capacitor is charged only when the logic levels of the input and output signals are not corresponding to a high-to-low transition of the input signal....
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