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Nanoparticles are attracting considerable interest as contrast agents for many different imaging modalities. Moreover, imaging the events at the cellular and molecular level is possible by using nanoparticles that have the desired targeting moiety. Unfortunately, ultrasound imaging cannot visualize the nano-structures directly due to its limited spatial resolution and contrast. We present a new technique,...
An intravascular ultrasound image reconstruction technique that combines synthetic aperture focusing and display pixel-based focusing methods is presented. Although the synthetic aperture focusing method can improve intravascular ultrasound image quality, the final displayed images are usually blurry in the angular direction due to the limitations of the digital scan converter. The display pixel-based...
Photoacoustic signals, detected by a transducer array, need to be beamformed for subsequent use in a limited view angle tomography such as B-scan imaging. In the presence of the light scattering or phase aberration, the spatial resolution and contrast in the photoacoustic images are degraded. Phase aberration due to tissues with inhomogeneous acoustic speeds is a major source for image degradation...
Combined ultrasound and photoacoustic imaging can be implemented using a standard ultrasound imaging system interfaced with a pulsed laser source. Since in both ultrasound and photoacoustic imaging modes the acoustic waves are measured at the surface of the tissue using an ultrasound transducer, the combined imaging system can utilize the same imaging probe. However, the generation mechanisms and,...
An advanced in-vivo imaging technology; namely, combined ultrasound, elasticity and photoacoustic imaging, capable of visualizing both structural and functional properties of living tissue, is presented. This hybrid imaging technology is based on the fusion of the complementary imaging modalities and takes full advantage of the many synergistic features of these systems. To highlight fundamental differences...
We investigated the performance of the conventional and high frame rate ultrasound imaging techniques for strain and elasticity imaging. High frame rate imaging is necessary to track fast deformation in elasticity imaging, but the ultrasound image quality is known to be compromised. Both numerical and experimental studies were performed using point targets and tissue mimicking phantoms. The results...
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