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A young patient with undefined autoimmune lymphoproliferative syndrome (ALPS-U) and low back pain underwent a CT and MRI study that showed enhancing vertebral lesions, some pulmonary nodules and diffuse latero-cervical lymphadenopathy. A 18 F-FDG-PET/CT scan showed many areas of intense 18 F-FDG uptake in multiple vertebrae, in some ribs, in the sacrum, in the liver, in both lungs,...